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About:
A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims
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An Entity of Type :
schema:ScholarlyArticle
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims
Creator
Rashid, Harunor
Barasheed, Osamah
Booy, Robert
El Bashir, Haitham
Haworth, Elizabeth
Heron, Leon
Nguyen-Van-Tam, Jonathan
Ridda, Iman
Wang, Mandy
Memish, Ziad
Holmes, Edward
Dwyer, Dominic
source
Elsevier; Medline; PMC
abstract
BACKGROUND: Cost-effective interventions are needed to control the transmission of viral respiratory tract infections (RTIs) in mass gatherings. Facemasks are a promising preventive measure, however, previous studies on the efficacy of facemasks have been inconclusive. This study proposes a large-scale facemask trial during the Hajj pilgrimage in Saudi Arabia and presents this protocol to illustrate its feasibility and to promote both collaboration with other research groups and additional relevant studies. METHODS/DESIGN: A cluster-randomised controlled trial is being conducted to test the efficacy of standard facemasks in preventing symptomatic and proven viral RTIs among pilgrims during the Hajj season in Mina, Mecca, Saudi Arabia. The trial will compare the ‘supervised use of facemasks’ versus ‘standard measures’ among pilgrims over several Hajj seasons. Cluster-randomisation will be done by accommodation tents with a 1:1 ratio. For the intervention tents, free facemasks will be provided to be worn consistently for 7 days. Data on flu-like symptoms and mask use will be recorded in diaries. Nasal samples will be collected from symptomatic recruits and tested for nucleic acid of respiratory viruses. Data obtained from questionnaires, diaries and laboratory tests will be analysed to examine whether mask use significantly reduces the frequency of laboratory-confirmed respiratory viral infection and syndromic RTI as primary outcomes. CONCLUSIONS: This trial will provide valuable evidence on the efficacy of standard facemask use in preventing viral respiratory tract infections at mass gatherings. This study is registered at the Australian New Zealand Clinical Trials Registry (ANZCTR), ACTRN: ACTRN12613001018707 (http://www.anzctr.org.au).
has issue date
2014-10-02
(
xsd:dateTime
)
bibo:doi
10.1016/j.jegh.2014.08.002
bibo:pmid
25922328
has license
no-cc
sha1sum (hex)
e279f4afd8d1def9b69ae41e53746314cee28af1
schema:url
https://doi.org/10.1016/j.jegh.2014.08.002
resource representing a document's title
A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims
has PubMed Central identifier
PMC7103985
has PubMed identifier
25922328
schema:publication
J Epidemiol Glob Health
resource representing a document's body
covid:e279f4afd8d1def9b69ae41e53746314cee28af1#body_text
is
schema:about
of
named entity 'preventing'
named entity 'RANDOMISED CONTROLLED TRIAL'
named entity 'LARGE'
named entity 'EFFICACY'
named entity 'STUDY'
named entity 'HAVE'
named entity 'EFFECTIVE INTERVENTIONS'
named entity 'PREVENTING'
named entity 'INCONCLUSIVE'
named entity 'CLUSTER'
named entity 'EFFICACY'
named entity 'TO TEST'
named entity 'RESPIRATORY VIRAL INFECTION'
named entity 'TO CONTROL'
named entity 'TRANSMISSION'
named entity 'MEASURE'
named entity 'NEEDED'
named entity 'PREVIOUS'
named entity 'PREVENTIVE'
named entity 'SCALE'
named entity 'RESPIRATORY TRACT INFECTIONS'
named entity 'STUDIES'
named entity 'BACKGROUND'
named entity 'HTTP'
named entity 'VIRAL'
named entity 'MASS'
named entity 'COST'
covid:arg/e279f4afd8d1def9b69ae41e53746314cee28af1
named entity 'viral'
named entity 'gatherings'
named entity 'transmission'
named entity 'respiratory tract infections'
named entity 'This'
named entity 'efficacy'
named entity 'randomised controlled trial'
named entity 'Hajj'
named entity 'MERS-CoV'
named entity 'viral infection'
named entity 'follow-up'
named entity 'influenza vaccination'
named entity 'Malaysia'
named entity 'Saudi Arabia'
named entity 'human metapneumovirus'
named entity 'Westmead'
named entity 'genomic sequencing'
named entity 'public health'
named entity 'viruses'
named entity 'antipyretics'
named entity 'Hajj'
named entity 'flu-like symptoms'
named entity 'Surgical Mask'
named entity 'intention-to-treat analysis'
named entity 'hand hygiene'
named entity 'Hajj'
named entity 'randomised trial'
named entity 'crowded places'
named entity 'viruses'
named entity 'barcode'
named entity 'Hajj'
named entity 'Hajj'
named entity 'Hajj'
named entity 'influenza'
named entity 'MERS CoV'
named entity 'Westmead Hospital'
named entity 'health education'
named entity 'respiratory infection'
named entity 'fever'
named entity 'Qatar'
named entity 'respiratory diseases'
named entity 'Turkey'
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