About: Venous thrombotic events in severe and critically COVID-19 patients despite high dose prophylactic low-molecular-weight heparin

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About: Venous thrombotic events in severe and critically COVID-19 patients despite high dose prophylactic low-molecular-weight heparin Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Venous thrombotic events in severe and critically COVID-19 patients despite high dose prophylactic low-molecular-weight heparin
Creator	Boer, Dirk Den Hollander, Jan El Moussaoui, Rachida Rachida El Moussaoui, ; Reinier, ; Sprenger, A Sprenger, Reinier Van Den Bout, Hans Visser, Chantal
Source	Elsevier; PMC
abstract	Abstract Hypercoagulation is one of the most distinct prognostic factors of patients with COVID-19 and has been associated with arterial thrombosis and other venous thrombotic events (VTE). Bleeding complications are far less encountered. The International Society on Thrombosis and Haemostasis (ISTH) guidance advises giving prophylactic low-molecular-weight heparin (LMWH) to prevent these events, although there is evidence that the incidence remains high despite using prophylactic LMWH. We describe three cases of COVID-19 pneumonia that were admitted to our intensive care unit (ICU) and developed acute pulmonary embolisms (APE) despite high dosage prophylactic LMWH. These cases raise concerns about using prophylactic LMWH instead of therapeutic anticoagulation in severe and critically COVID-19 patients.
has issue date	2020-08-19(xsd:dateTime)
bibo:doi	10.1016/j.tru.2020.100006
has license	els-covid
sha1sum (hex)	e3d656868a307e0b4e0ba50e5f61d1de83e37b54
schema:url	https://doi.org/10.1016/j.tru.2020.100006
resource representing a document's title	Venous thrombotic events in severe and critically COVID-19 patients despite high dose prophylactic low-molecular-weight heparin
has PubMed Central identifier	PMC7434635
resource representing a document's body	covid:e3d656868a307e0b4e0ba50e5f61d1de83e37b54#body_text
is schema:about of	named entity 'patients' named entity 'APE' named entity 'COVID-19' named entity 'Bleeding' named entity 'Journal' named entity 'patients' named entity 'prophylactic' named entity 'PROPHYLACTIC' named entity 'IMMUNE' named entity 'INTENSIVE CARE UNIT' named entity 'COMPLICATIONS' named entity 'DESCRIBE' named entity 'ONE OF' named entity 'factors' named entity 'prophylactic' named entity 'potential' named entity 'prophylactic' named entity 'events' named entity 'raise' named entity 'high' named entity 'patients' named entity 'severe' named entity 'high' named entity 'VTE' named entity 'LMWH' named entity 'intensive care unit' named entity 'thrombotic complications' named entity 'pneumonia' named entity 'prophylactic' named entity 'COVID-19' named entity 'COVID-19' named entity 'thrombotic events' named entity 'prophylaxis' named entity 'patients' named entity 'vicious cycle' named entity 'thrombotic complications' named entity 'ultrasound' named entity '0.9' named entity 'Il-6' named entity 'infection' named entity 'ultrasound' named entity 'antigen test' named entity 'LMWH' named entity 'upper extremities' named entity 'hypercoagulable state' named entity 'hypercoagulation' named entity 'COVID' named entity 'chest X-ray' named entity '1, 2' named entity 'innate immunity' named entity 'dalteparin' named entity 'intubated' named entity 'thrombotic complications' named entity 'prophylactic' named entity 'LMWH' named entity 'hypercoagulable state' named entity 'sinus' named entity 'COVID' named entity 'randomized controlled trials' named entity 'prophylaxis' named entity 'myocardial infarction' named entity 'oxygen' named entity 'prophylactic' named entity 'COVID-19' named entity 'central venous catheter' named entity 'chest X-ray' named entity 'medical history' named entity 'ICU' named entity 'hypercoagulable state' named entity 'COVID-19' named entity 'platelets' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'VTE' named entity 'anticoagulation' named entity 'SARS-CoV-2'

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