About: Challenges for Microelectronics in Non-Invasive Medical Diagnostics

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Challenges for Microelectronics in Non-Invasive Medical Diagnostics
Creator	Carminati, Marco Fiorini, Carlo
Source	PMC
abstract	Microelectronics is emerging, sometimes with changing fortunes, as a key enabling technology in diagnostics. This paper reviews some recent results and technical challenges which still need to be addressed in terms of the design of CMOS analog application specific integrated circuits (ASICs) and their integration in the surrounding systems, in order to consolidate this technological paradigm. Open issues are discussed from two, apparently distant but complementary, points of view: micro-analytical devices, combining microfluidics with affinity bio-sensing, and gamma cameras for simultaneous multi-modal imaging, namely scintigraphy and magnetic resonance imaging (MRI). The role of integrated circuits is central in both application domains. In portable analytical platforms, ASICs offer miniaturization and tackle the noise/power dissipation trade-off. The integration of CMOS chips with microfluidics poses multiple open technological issues. In multi-modal imaging, now that the compatibility of the acquisition chains (thousands of Silicon Photo-Multipliers channels) of gamma detectors with Tesla-level magnetic fields has been demonstrated, other development directions, enabled by microelectronics, can be envisioned in particular for single-photon emission tomography (SPECT): a faster and simplified operation, for instance, to allow transportable applications (bed-side) and hardware pre-processing that reduces the number of output signals and the image reconstruction time.
has issue date	2020-06-29(xsd:dateTime)
bibo:doi	10.3390/s20133636
bibo:pmid	32610430
has license	cc-by
sha1sum (hex)	e41ef8fb9ea0a8c6abd2159fd94d12a86267806d
schema:url	https://doi.org/10.3390/s20133636
resource representing a document's title	Challenges for Microelectronics in Non-Invasive Medical Diagnostics
has PubMed Central identifier	PMC7374509
has PubMed identifier	32610430
schema:publication	Sensors (Basel)
resource representing a document's body	covid:e41ef8fb9ea0a8c6abd2159fd94d12a86267806d#body_text
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