About: Viable Influenza A Virus in Airborne Particles from Human Coughs

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viable Influenza A Virus in Airborne Particles from Human Coughs
Creator	Othumpangat, Sreekumar Martin, Stephen Beezhold, Donald Blachere, Francoise Lindsley, William Noti, John Clark, Karen Palmer, Jan Goldsmith, William Noorbakhsh, Bahar Thewlis, Robert Vishnu, Abhishek
Source	PMC
abstract	Patients with influenza release aerosol particles containing the virus into their environment. However, the importance of airborne transmission in the spread of influenza is unclear, in part because of a lack of information about the infectivity of the airborne virus. The purpose of this study was to determine the amount of viable influenza A virus that was expelled by patients in aerosol particles while coughing. Sixty-four symptomatic adult volunteer outpatients were asked to cough 6 times into a cough aerosol collection system. Seventeen of these participants tested positive for influenza A virus by viral plaque assay (VPA) with confirmation by viral replication assay (VRA). Viable influenza A virus was detected in the cough aerosol particles from 7 of these 17 test subjects (41%). Viable influenza A virus was found in the smallest particle size fraction (0.3 μm to 8 μm), with a mean of 142 plaque-forming units (SD 215) expelled during the 6 coughs in particles of this size. These results suggest that a significant proportion of patients with influenza A release small airborne particles containing viable virus into the environment. Although the amounts of influenza A detected in cough aerosol particles during our experiments were relatively low, larger quantities could be expelled by influenza patients during a pandemic when illnesses would be more severe. Our findings support the idea that airborne infectious particles could play an important role in the spread of influenza.
has issue date	2014-12-18(xsd:dateTime)
bibo:doi	10.1080/15459624.2014.973113
bibo:pmid	25523206
has license	no-cc
sha1sum (hex)	e53cb064f9b6b5061f0d38c4a7012562675643e6
schema:url	https://doi.org/10.1080/15459624.2014.973113
resource representing a document's title	Viable Influenza A Virus in Airborne Particles from Human Coughs
has PubMed Central identifier	PMC4734406
has PubMed identifier	25523206
schema:publication	J Occup Environ Hyg
resource representing a document's body	covid:e53cb064f9b6b5061f0d38c4a7012562675643e6#body_text
is schema:about of	named entity 'particles' named entity 'particles' named entity 'participants' named entity 'airborne' named entity 'influenza' named entity 'Human' named entity 'PARTICLE SIZE' named entity 'ASSAY' named entity 'SEVENTEEN' named entity 'SIGNIFICANT' named entity 'IMPORTANT' named entity 'IDEA' named entity 'TESTED' named entity 'PANDEMIC' named entity 'ROLE' named entity 'INFECTIOUS' named entity 'COUGH' named entity 'CONTAINING' named entity 'PURPOSE' named entity 'DETECTED' named entity 'INFLUENZA' named entity 'VIRAL REPLICATION' named entity 'expelled' named entity 'viral replication' named entity 'volunteer' named entity 'influenza' named entity 'illnesses' named entity 'study' named entity 'influenza A virus' named entity 'virus' named entity 'Virus' named entity 'Influenza A' named entity 'influenza' named entity 'coughing' named entity 'aerosol' named entity 'cough' named entity 'viral plaque' named entity 'aerosol particles' named entity 'airborne transmission' named entity 'virus' named entity 'influenza' named entity 'virus' named entity 'Influenza A Virus' named entity 'particles' named entity 'viruses' named entity 'health care facilities' named entity 'cough' named entity 'relative risk' named entity 'cDNA' named entity 'MagMax' named entity 'cough' named entity 'ketone' named entity 'SKC' named entity 'influenza' named entity 'Grand Island, NY' named entity 'Dulbecco's modified Eagle's medium' named entity 'Airborne particles' named entity 'PCR-based methods' named entity 'cough' named entity 'virus' named entity 'disinfection' named entity 'influenza' named entity 'Yorba Linda' named entity 'influenza' named entity 'aerosol' named entity 'infection control' named entity 'influenza A virus' named entity 'cough' named entity 'influenza' named entity 'aerosol particles'

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