About: Outcomes of COVID-19 among Patients on In-Center Hemodialysis: An Experience from the Epicenter in South Korea

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Outcomes of COVID-19 among Patients on In-Center Hemodialysis: An Experience from the Epicenter in South Korea
Creator	Kim, Yong-Lim Lee, Jaehee Chang, Hyun-Ha Kim, Shin-Woo Kim, Seong Cho, Jang-Hee Choi, Ji-Young Jung, Hee-Yeon Kang, Seok Kim, Chan-Duck Lee, Yong-Hoon Lim, Jeong-Hoon Park, Sun-Hee
source	Medline; PMC
abstract	Patients with advanced chronic kidney disease (CKD) or who are on hemodialysis (HD) could have increased susceptibility to the 2019 coronavirus disease (COVID-19) given their pre-existing comorbidities, older age, compromised immune system, and regular visits to populated outpatient dialysis centers. This study included 14 consecutive patients on HD or with advanced CKD who initiated HD after being diagnosed with laboratory-confirmed COVID-19 from February to April 2020 in hospitals throughout Daegu, South Korea. The included patients, 42.9% of whom were men, had a mean age of 63.5 years. Four patients had a history of contact with a patient suffering from COVID-19. The most common symptom was cough (50.0%), followed by dyspnea (35.7%). The mean time from symptom onset to diagnosis and admission was 2.6 and 3.5 days, respectively. Patients exhibited lymphopenia and elevated inflammatory markers, including C-reactive protein and ferritin. Chest radiography findings showed pulmonary infiltration in 10 patients. All patients underwent regular HD in a negative pressure room and received antiviral agents. Four patients received mechanical ventilation and continuous renal replacement therapy at a median duration of 14.0 and 8.5 days, respectively. One patient underwent extracorporeal membrane oxygenation for three days. Among the 14 patients included, two died due to acute respiratory distress syndrome, nine were discharged from the hospital, and three remained hospitalized. Despite the high-risk conditions associated with worse outcomes, patients on HD did not exhibit extremely poor overall COVID-19 outcomes perhaps due to early diagnosis, prompt hospitalization, and antiviral therapy.
has issue date	2020-06-02(xsd:dateTime)
bibo:doi	10.3390/jcm9061688
bibo:pmid	32498262
has license	cc-by
sha1sum (hex)	e7d888de43d604ddfc22b64be8bfd1bf59993630
schema:url	https://doi.org/10.3390/jcm9061688
resource representing a document's title	Outcomes of COVID-19 among Patients on In-Center Hemodialysis: An Experience from the Epicenter in South Korea
has PubMed Central identifier	PMC7355817
has PubMed identifier	32498262
schema:publication	J Clin Med
resource representing a document's body	covid:e7d888de43d604ddfc22b64be8bfd1bf59993630#body_text
is schema:about of	named entity 'South Korea' named entity 'Vital signs' named entity 'high-risk' named entity 'hydroxychloroquine' named entity 'clinical features' named entity 'C-reactive protein' named entity 'Clinical outcomes' named entity '8.5' named entity 'dialysis' named entity 'COVID' named entity 'antiviral agents' named entity 'Kolmogorov-Smirnov test' named entity 'SARS-CoV-2' named entity 'disease transmission' named entity 'case report' named entity 'acute respiratory distress syndrome' named entity 'clinical characteristics' named entity 'dialysis' named entity 'Daegu' named entity 'lymphopenia' named entity 'lactate dehydrogenase' named entity 'continuous renal replacement therapy' named entity 'extracorporeal membrane oxygenation' named entity 'COVID-19' named entity '3.5' named entity 'inflammatory responses' named entity 'adaptive immunity' named entity 'gastrointestinal symptoms' named entity 'comorbidities' named entity 'symptom' named entity 'COVID' named entity 'mechanical ventilation' named entity 'severe pneumonia' named entity 'respiratory symptoms' named entity 'Informed consent' named entity 'symptom' named entity 'procalcitonin' named entity 'diarrhea' named entity 'hemodialysis' named entity 'ritonavir' named entity 'COVID-19' named entity 'standard deviations' named entity 'procalcitonin' named entity 'social distancing' named entity 'tachypnea' named entity 'COVID-19 pandemic' named entity 'platelet count' named entity 'early diagnosis' named entity 'clinical characteristics' named entity 'COVID' named entity 'quarantine' named entity 'symptom' named entity '8.5' named entity 'mmHg' named entity '21.4%' named entity '21.4%' named entity 'interquartile range' named entity 'Wuhan' named entity 'intravenous immunoglobulin' named entity 'fever' named entity 'COVID-19' named entity 'positive COVID-19 test' named entity 'intensive care unit' named entity 'Daegu' named entity 'hypertension' named entity '4.7' named entity '21.4%' named entity 'lactate dehydrogenase' named entity 'dialysis'

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