About: Harnessing nanoparticles for immune modulation

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Harnessing nanoparticles for immune modulation
Creator	King, Nicholas Getts, Daniel Miller, Stephen Shea, Lonnie
Source	Elsevier; Medline; PMC
abstract	Recent approaches using nanoparticles engineered for immune regulation have yielded promising results in preclinical models of disease. The number of nanoparticle therapies is growing, fueled by innovations in nanotechnology and advances in understanding of the underlying pathogenesis of immune-mediated diseases. In particular, recent mechanistic insight into the ways in which nanoparticles interact with the mononuclear phagocyte system and impact its function during homeostasis and inflammation have highlighted the potential of nanoparticle-based therapies for controlling severe inflammation while concurrently restoring peripheral immune tolerance in autoimmune disease. Here we review recent advances in nanoparticle-based approaches aimed at immune-modulation, and discuss these in the context of concepts in polymeric nanoparticle development, including particle modification, delivery and the factors associated with successful clinical deployment.
has issue date	2015-07-01(xsd:dateTime)
bibo:doi	10.1016/j.it.2015.05.007
bibo:pmid	26088391
has license	green-oa
sha1sum (hex)	e9370c9cd0eaea1b0c211c41d7d3718042a444ee
schema:url	https://doi.org/10.1016/j.it.2015.05.007
resource representing a document's title	Harnessing nanoparticles for immune modulation
has PubMed Central identifier	PMC4603374
has PubMed identifier	26088391
schema:publication	Trends in Immunology
resource representing a document's body	covid:e9370c9cd0eaea1b0c211c41d7d3718042a444ee#body_text
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