About: Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives

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About: Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives
Creator	Barbakadze, N Kakhabrishvili, M Makhmudov, U Nadaraia, N Pichette, A Sylla, B Yunusov, S
Source	Medline; PMC
abstract	Several new N-containing epiandrosterone derivatives modified by phenylacetic acid chloride were synthesized for biological activity studies. Compounds with antiviral activity were discovered among them and 3β-hydroxy-1′-aryl-3′-methyl-5′-androstano[17,16-d]pyrazolines prepared by us earlier.
has issue date	2018-04-14(xsd:dateTime)
bibo:doi	10.1007/s10600-018-2330-2
bibo:pmid	32214425
has license	no-cc
sha1sum (hex)	e9d0bd1ed39a0fa7aa4a623b71111667a3dae461
schema:url	https://doi.org/10.1007/s10600-018-2330-2
resource representing a document's title	Synthesis and Biological Activity of Several Modified 5α-Androstanolone Derivatives
has PubMed Central identifier	PMC7087839
has PubMed identifier	32214425
schema:publication	Chem Nat Compd
resource representing a document's body	covid:e9d0bd1ed39a0fa7aa4a623b71111667a3dae461#body_text
is schema:about of	named entity 'derivatives' named entity 'BIOLOGICAL ACTIVITY' named entity 'EPIANDROSTERONE' named entity 'EARLIER' named entity 'CONTAINING' named entity 'HYDROXY' named entity 'SYNTHESIZED' named entity 'ANDROSTANOLONE' named entity 'PHENYLACETIC ACID' named entity 'ACID CHLORIDE' named entity 'STUDIES' named entity 'PREPARED' named entity 'METHYL' named entity 'ANTIVIRAL ACTIVITY' named entity 'MODIFIED BY' named entity 'BIOLOGICAL ACTIVITY' named entity 'NEW' named entity 'MODIFIED' named entity 'SYNTHESIS' covid:arg/e9d0bd1ed39a0fa7aa4a623b71111667a3dae461 named entity 'antiviral' named entity 'prepared' named entity 'chloride' named entity 'studies' named entity 'chloride' named entity 'epiandrosterone' named entity 'steroids' named entity 'EtOH' named entity 'MDCK' named entity 'Antiviral activity' named entity 'X-ray crystal structure analysis' named entity 'Bruker' named entity 'Respiratory syncytial virus' named entity 'CDCl' named entity 'virus' named entity 'steroids' named entity 'cell culture' named entity 'protons' named entity 'Dengue virus' named entity 'hydrazone' named entity 'cell culture' named entity 'HPLC' named entity 'antiviral' named entity 'ppm' named entity 'C NMR' named entity 'Cambridge Crystallographic Data Centre' named entity 'Melting points' named entity 'atom' named entity 'cell culture' named entity 'least-squares' named entity 'virus' named entity 'NMR spectrum' named entity 'cell culture' named entity '1.2' named entity 'cell culture' named entity 'NMR' named entity 'protons' named entity 'mmol' named entity 'Hydrazones' named entity 'pyrazoline' named entity 'IR spectra' named entity 'antiviral activity' named entity 'pregnenolone' named entity 'proton' named entity 'phenylacetic acid' named entity 'epiandrosterone' named entity 'ketone' named entity 'NAGEMA' named entity 'diffractometer' named entity 'Polio virus' named entity 'chloride' named entity 'hydrazone' named entity 'IR spectrum' named entity '1.2' named entity 'CCDC'

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