About: Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study

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About: Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study
Creator	Del, María Lardelli-Claret, Pablo Martínez-Diz, Silvia Martínez-Ruiz, Virginia Valero-Ubierna, Carmen Belé, Ana Cabrero-Rodríguez, Celia García-Martín, Miguel Guirado-Ruiz, Pedro Gá Mez-Baeza, Pablo Inez-Ramos-Bossini, Lá Jesú, Antonio Jimé Nez-Mejías, Eladio Luis, Juan Luis, Miguel Mancera-Romero, José Martín-Delosreyesid, Martín-Romero, Divina Miz-Molina, Gá Ngel Ferná Ndez-García, Miguel Nicolá S Barba-Gyengo, Rivera-Izquierdo Id, Mario Rodríguez-Camacho, Marta Sá Nchez-Pé Rez, Rosa Tahery-Mahmoud, Arezu
Source	Medline; PMC
abstract	BACKGROUND: To identify and quantify associations between baseline characteristics on hospital admission and mortality in patients with COVID-19 at a tertiary hospital in Spain. METHODS AND FINDINGS: This retrospective case series included 238 patients hospitalized for COVID-19 at Hospital Universitario Clínico San Cecilio (Granada, Spain) who were discharged or who died. Electronic medical records were reviewed to obtain information on sex, age, personal antecedents, clinical features, findings on physical examination, and laboratory results for each patient. Associations between mortality and baseline characteristics were estimated as hazard ratios (HR) calculated with Cox regression models. Series mortality was 25.6%. Among patients with dependence for basic activities of daily living, 78.7% died, and among patients residing in retirement homes, 80.8% died. The variables most clearly associated with a greater hazard of death were age (3% HR increase per 1-year increase in age; 95%CI 1–6), diabetes mellitus (HR 2.42, 95%CI 1.43–4.09), SatO(2)/FiO(2) ratio (43% HR reduction per 1-point increase; 95%CI 23–57), SOFA score (19% HR increase per 1-point increase, 95%CI 5–34) and CURB-65 score (76% HR increase per 1-point increase, 95%CI 23–143). CONCLUSIONS: The patients residing in retirement homes showed great vulnerability. The main baseline factors that were independently associated with mortality in patients hospitalized for COVID-19 were older age, diabetes mellitus, low SatO(2)/FiO(2) ratio, and high SOFA and CURB-65 scores.
has issue date	2020-06-25(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0235107
bibo:pmid	32584868
has license	cc-by
sha1sum (hex)	eac222eafac840080046008275d66b0fd8ab9004
schema:url	https://doi.org/10.1371/journal.pone.0235107
resource representing a document's title	Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study
has PubMed Central identifier	PMC7316360
has PubMed identifier	32584868
schema:publication	PLoS One
resource representing a document's body	covid:eac222eafac840080046008275d66b0fd8ab9004#body_text
is schema:about of	named entity 'identify' named entity 'retrospective' named entity 'PATIENTS' named entity 'COVID-19' named entity 'HOSPITAL ADMISSION' named entity 'mortality' named entity 'admission' named entity 'hospital' named entity 'laboratory' named entity 'tertiary hospital' named entity 'COVID-19' named entity 'Spain' named entity 'observational study' named entity 'SOFA score' named entity 'frequency distribution' named entity 'tiredness' named entity 'hospital emergency' named entity 'lactate dehydrogenase' named entity 'evolution' named entity 'missing data' named entity 'PCR test' named entity 'chronic diseases' named entity 'pneumonia' named entity 'Spain' named entity 'older age' named entity 'odds ratio' named entity 'mortality rate' named entity 'SARS' named entity 'Spain' named entity 'fever' named entity 'lymphocyte count' named entity 'infection' named entity 'independent variables' named entity 'malaise' named entity 'physical exam' named entity 'haemoptysis' named entity 'standard deviation' named entity 'China' named entity 'morbidity' named entity 'follow-up' named entity '2, 3' named entity '16.6' named entity 'hilar' named entity 'gastrointestinal symptoms' named entity 'neutrophilia' named entity 'prognosis' named entity 'D-dimer' named entity 'exanthema' named entity 'COVID-19' named entity 'oxygen' named entity 'productive cough' named entity 'oxygen' named entity 'procalcitonin' named entity 'haemoglobin' named entity 'China' named entity 'IL-10' named entity 'arterial blood'

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