About: Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients
Creator	Wang, Wei Wang, Yan Hu, Bicheng Liu, Yun Hu, Zhibin Chen, Guohua Song, Ci Xia, Ping Li, Chaojun Li, Weiqin Yang, Xiaoyu Yao, Bing
source	MedRxiv
abstract	Background: As of March 11, 2020, the COVID-19 outbreak was declared as a pandemic. Expending our understanding of the transmission routes of the viral infection is crucial in controlling the outbreak. It is unclear whether the 2019 novel coronavirus (2019-nCoV) can directly infect the testes or male genital tract and be sexually transmitted from males. Methods: From January 31 to March 14, 2020, 12 patients in recovery and one patient died of COVID-19 were included in this descriptive study. The clinical characteristics, laboratory findings, chest CT scans and outcome data were recorded. To examine whether there is sexual transmission from male, we employed realtime polymerase chain reaction testing (RT-PCR) to detect 2019-nCov in semen or testicular biopsy specimen. Findings: The age range of the 12 patients in recovery was 22-38 years. None of the patients developed severe COVID-19 pneumonia. As of March 14, 2020, ten patients discharged from the hospital while the rest 2 had developed into recovery stage. All of the patients in recovery tested negative for 2019-nCoV RNA in semen samples. Another died patient was 67 years old, who died in March 10, 2020 and tissue sample via testicular biopsy was tested negative for viral RNA. Conclusion: No positive RT-PCR result was found in the semen or testicular biopsy specimen. The results from this study show no evidence of sexual transmission of 2019-nCov from males.
has issue date	2020-04-04(xsd:dateTime)
bibo:doi	10.1101/2020.03.31.20042333
has license	medrxiv
sha1sum (hex)	eb2fcc2195311a3c24f9bef3ff4166e329f69355
schema:url	https://doi.org/10.1101/2020.03.31.20042333
resource representing a document's title	Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients
resource representing a document's body	covid:eb2fcc2195311a3c24f9bef3ff4166e329f69355#body_text
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