About: Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance

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About: Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance
Creator	Takano, Tomomi Shi, Da Yabe, Shizuka Higuchi, Wataru Nishiyama, Akihito »more»
source	PMC
abstract	Methicillin-resistant Staphylococcus aureus (MRSA) is able to persist not only in hospitals (with a high level of antimicrobial agent use) but also in the community (with a low level of antimicrobial agent use). The former is called hospital-acquired MRSA (HA-MRSA) and the latter community-acquired MRSA (CA-MRSA). It is believed MRSA clones are generated from S. aureus through insertion of the staphylococcal cassette chromosome mec (SCCmec), and outbreaks occur as they spread. Several worldwide and regional clones have been identified, and their epidemiological, clinical, and genetic characteristics have been described. CA-MRSA is likely able to survive in the community because of suitable SCCmec types (type IV or V), a clone-specific colonization/infection nature, toxin profiles (including Pantone-Valentine leucocidin, PVL), and narrow drug resistance patterns. CA-MRSA infections are generally seen in healthy children or young athletes, with unexpected cases of diseases, and also in elderly inpatients, occasionally surprising clinicians used to HA-MRSA infections. CA-MRSA spreads within families and close-contact groups or even through public transport, demonstrating transmission cores. Re-infection (including multifocal infection) frequently occurs, if the cores are not sought out and properly eradicated. Recently, attention has been given to CA-MRSA (USA300), which originated in the US, and is growing as HA-MRSA and also as a worldwide clone. CA-MRSA infection in influenza season has increasingly been noted as well. MRSA is also found in farm and companion animals, and has occasionally transferred to humans. As such, the epidemiological, clinical, and genetic behavior of CA-MRSA, a growing threat, is focused on in this study.
has issue date	2010-03-25(xsd:dateTime)
bibo:doi	10.1007/s10156-010-0045-9
bibo:pmid	20336341
has license	no-cc
sha1sum (hex)	ee715aa6e08aff0d312956f8668d5c22d1366223
schema:url	https://doi.org/10.1007/s10156-010-0045-9
resource representing a document's title	Community-acquired methicillin-resistant Staphylococcus aureus: community transmission, pathogenesis, and drug resistance
has PubMed Central identifier	PMC7088255
has PubMed identifier	20336341
schema:publication	J Infect Chemother
resource representing a document's body	covid:ee715aa6e08aff0d312956f8668d5c22d1366223#body_text
is schema:about of	named entity 'transmission' named entity 'Community-acquired' named entity 'drug resistance' named entity 'clindamycin' named entity 'PSMb2' »more»

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