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About:
Teschovirus
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
New Facet based on Instances of this Class
Attributes
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Teschovirus
Creator
Dhama, Kuldeep
Bhat, Sudipta
Ghosh, Souvik
Vlasova, Anastasia
Touil, Nadia
Wang, Fun-In
Ghosh, S
Malik, Y
Singh,
Singh, Yashpal
Yadav, M
Wang, F.-I
Bhat, S
Dhama, ·
Mahendra, Pal
Patel, Sardar
Singh, ·
Vlasova, A
Yadav, Raj
Source
PMC
abstract
Teschoviruses are emerging pathogens, belonging to the family Picornaviridae, and infects porcine population only. Among all, porcine teschoviruses (PTVs) are of high prominence leading to clinical illness and consequent economic loss to the livestock sector. These are associated with extremely lethal non-suppurative polioencephalomyelitis (Teschen disease) and are distributed world over. Its milder form, Talfan disease, inflicts low morbidity and mortality and general clinical disease. The first epizootics of Teschen disease occurred in 1929 in the Czech Republic. Mature virions are small (23–30 nm) and stable in environmental conditions (pH range 2–9, heat, lipid solvents). Genetic variations in the major surface protein, VP1, lead to the evolution of several new types. As of now, 13 genotypes in PTV are approved, namely PTV-1–13. Among all, PTV-1 is highly virulent and causes severe mortality and morbidity in the porcine population, domestic as well as wild. Ingestion is the main spreading route of infection, though intra-nasal infection and virus secretion in the urine are also noted. Along with encephalitis, PTVs are also responsible for reproductive disorders, diarrhoea, pneumonia, pericarditis and myocarditis. PTVs are also found as co-infection with several bacterial, viral and parasitic pathogens. Several conventional and modern diagnostics tools are available for their detection. Alternative of serological typing, VP1 and VP2 gene-based molecular typing is now preferred to know the epidemiological pattern. Although initially vaccines were used for its eradication in Europe, due to the sporadic reports of mild PTV infection in several countries, the approach was discontinued. Moreover, due to the presence of multiple serotypes, developing a multivalent PTV vaccine to protect against all strains is a major challenge.
has issue date
2020-02-23
(
xsd:dateTime
)
bibo:doi
10.1007/978-981-15-0402-0_6
has license
no-cc
sha1sum (hex)
eea99edd3e46e56abb812a2b60448ce72dbe1270
schema:url
https://doi.org/10.1007/978-981-15-0402-0_6
resource representing a document's title
Teschovirus
has PubMed Central identifier
PMC7123469
schema:publication
Emerging and Transboundary Animal Viruses
resource representing a document's body
covid:eea99edd3e46e56abb812a2b60448ce72dbe1270#body_text
is
schema:about
of
named entity 'livestock'
named entity 'Picornaviridae'
named entity 'CLINICAL'
named entity 'THESE'
named entity 'LEAD'
named entity 'GENETIC VARIATIONS'
named entity 'PORCINE TESCHOVIRUSES'
named entity 'TESCHEN DISEASE'
named entity 'HIGH'
named entity 'SECTOR'
named entity 'PATHOGENS'
named entity 'LOW'
named entity 'SUPPURATIVE'
named entity 'EXTREMELY'
named entity 'RANGE 2'
named entity 'TALFAN DISEASE'
named entity 'MORBIDITY AND MORTALITY'
named entity 'BELONGING'
named entity 'ASSOCIATED WITH'
named entity 'HEAT'
named entity 'LETHAL'
named entity 'FORM'
named entity 'ILLNESS'
named entity 'LIVESTOCK'
named entity 'POPULATION'
named entity 'MAJOR'
named entity 'SURFACE PROTEIN'
named entity 'CZECH REPUBLIC'
named entity 'WORLD'
named entity 'EPIZOOTICS'
named entity 'CONDITIONS'
named entity 'POLIOENCEPHALOMYELITIS'
named entity 'CONSEQUENT'
named entity 'EVOLUTION'
named entity 'NON-'
named entity 'FAMILY PICORNAVIRIDAE'
named entity 'ECONOMIC LOSS'
named entity 'INFECTS'
named entity 'VIRIONS'
named entity 'SOLVENTS'
named entity 'LEADING'
named entity 'SMALL'
named entity 'NEW'
named entity 'ENVIRONMENTAL'
named entity 'LIPID'
named entity 'DISEASE'
named entity 'STABLE'
named entity 'CHAPTER'
named entity 'TESCHOVIRUS'
named entity 'MATURE'
named entity 'VP1'
named entity 'GENERAL'
named entity 'PROMINENCE'
named entity 'DISTRIBUTED'
named entity 'ITS'
named entity 'OCCURRED'
named entity 'PORCINE'
named entity 'TYPES'
named entity 'disease'
named entity 'extremely'
named entity 'belonging'
named entity 'evolution'
named entity 'morbidity'
named entity 'evolution'
named entity 'porcine'
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