About: COVID-19 and Stroke: incidence and etiological description in a high-volume center.

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About: COVID-19 and Stroke: incidence and etiological description in a high-volume center. Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 and Stroke: incidence and etiological description in a high-volume center.
Creator	Requena, Manuel Rubiera, Marta Ribo, Marc Boned, Sandra Deck, Matías García-Tornel Md¹ ³ ´, Álvaro García-Tornel, Alvaro García-Tornel, Álvaro Hernández, David Juega Md¹ ³ ´, Jesús Juega, Jesús Md², Alejandro Molina, Carlos Muchada, Marian Olivé, Marta Pagola, Jorge Piñana, Carlos Rodríguez-Luna, David Rodríguez-Villatoro, Noelia Tomasello, Alejandro
Source	Elsevier; PMC
abstract	BACKGROUND: An increased rate of thrombotic events has been associated to Coronavirus Disease 19 (COVID-19) with a variable rate of acute stroke. Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist. METHODS: We performed a single-center analysis of a prospective mandatory database. We studied all patients with confirmed COVID-19 and stroke diagnoses from March 2(nd) to April 30(th). Demographic, clinical, and imaging data were prospectively collected. Final diagnosis was determined after full diagnostic work-up unless impossible due to death. RESULTS: Of 2050 patients with confirmed SARS-CoV-2 infection, 21 (1.02%) presented an acute ischemic stroke 21 and 4 (0.2%) suffered an intracranial hemorrhage. After the diagnostic work-up, in 60.0% ischemic and all hemorrhagic strokes patients an etiology non-related with COVID-19 was identified. Only in 6 patients the stroke cause was considered possibly related to COVID-19, all of them required mechanical ventilation before stroke onset. Ten patients underwent endovascular treatment; compared with patients who underwent EVT in the same period, COVID-19 was an independent predictor of in-hospital mortality (50% versus 15%; Odds Ratio, 6.67; 95% CI, 1.1-40.4; p 0.04). CONCLUSIONS: The presence of acute stroke in patients with COVID-19 was below 2% and most of them previously presented established stroke risk factors. Without other potential cause, stroke was an uncommon complication and exclusive of patients with a severe pulmonary injury. The presence of COVID-19 in patients who underwent EVT was an independent predictor of in-hospital mortality.
has issue date	2020-08-05(xsd:dateTime)
bibo:doi	10.1016/j.jstrokecerebrovasdis.2020.105225
has license	no-cc
sha1sum (hex)	ef07fbe4e6680ae594a4b438a1e3cacc10a3fd86
schema:url	https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105225
resource representing a document's title	COVID-19 and Stroke: incidence and etiological description in a high-volume center.
has PubMed Central identifier	PMC7405833
schema:publication	J Stroke Cerebrovasc Dis
resource representing a document's body	covid:ef07fbe4e6680ae594a4b438a1e3cacc10a3fd86#body_text
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