About: Fatality risks for nosocomial outbreaks of Middle East respiratory syndrome coronavirus in the Middle East and South Korea

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About: Fatality risks for nosocomial outbreaks of Middle East respiratory syndrome coronavirus in the Middle East and South Korea Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Fatality risks for nosocomial outbreaks of Middle East respiratory syndrome coronavirus in the Middle East and South Korea
Creator	Hu, Yan Li, Yuan Liu, Shelan Chen, • Geng, • Ren, Yajin Sha, Jianping Zhang, Zhiruo
Source	Medline; PMC
abstract	Middle East respiratory syndrome coronavirus (MERS-CoV) was first isolated in 2012. The largest known outbreak outside the Middle East occurred in South Korea in 2015. As of 29 June 2016, 1769 laboratory-confirmed cases (630 deaths; 35.6 % case fatality rate [CFR]) had been reported from 26 countries, particularly in the Middle East. However, the CFR for hospital outbreaks was higher than that of family clusters in the Middle East and Korea. Here, we compared the mortality rates for 51 nosocomial outbreaks in the Middle East and one outbreak of MERS-CoV in South Korea. Our findings showed the CFR in the Middle East was much higher than that in South Korea (25.9 % [56/216] vs. 13.8 % [24/174], p = 0.003). Infected individuals who died were, on average, older than those who survived in both the Middle East (64 years [25–98] vs. 46 years [2–85], p = 0.000) and South Korea (68 years [49–82] vs. 53.5 years [16–87], p = 0.000). Similarly, the co-morbidity rates for the fatal cases were statistically higher than for the nonfatal cases in both the Middle East (64.3 % [36/56] vs. 28.1 % [45/160], p = 0.000) and South Korea (45.8 % [11/24] vs. 12.0 % [18/150], p = 0.000). The median number of days from onset to confirmation of infection in the fatal cases was longer than that for survivors from the Middle East (8 days [1–47] vs. 4 days [0–14], p = 0.009). Thus, older age, pre-existing concurrent diseases, and delayed confirmation increase the odds of a fatal outcome in nosocomial MERS-CoV outbreaks in the Middle East and South Korea. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-016-3062-x) contains supplementary material, which is available to authorized users.
has issue date	2016-09-23(xsd:dateTime)
bibo:doi	10.1007/s00705-016-3062-x
bibo:pmid	27664026
has license	no-cc
sha1sum (hex)	ef1524eed8ca8fad7b96301b586cafc72d15ef04
schema:url	https://doi.org/10.1007/s00705-016-3062-x
resource representing a document's title	Fatality risks for nosocomial outbreaks of Middle East respiratory syndrome coronavirus in the Middle East and South Korea
has PubMed Central identifier	PMC7087023
has PubMed identifier	27664026
schema:publication	Arch Virol
resource representing a document's body	covid:ef1524eed8ca8fad7b96301b586cafc72d15ef04#body_text
is schema:about of	named entity 'South Korea' named entity 'South Korea' named entity 'outbreaks' named entity 'confirmation' named entity '2016' named entity 'SOUTH KOREA' named entity 'INCREASE' named entity 'MORTALITY RATES' named entity 'KNOWN' named entity 'ARTICLE' named entity '28630' named entity 'DEATHS' named entity 'INFECTION' named entity '35.6' named entity 'CLUSTERS' named entity 'FAMILY' named entity 'OUTBREAKS' named entity '2015' named entity 'CASES' named entity 'YEARS' named entity '288' named entity 'HERE' named entity 'CONFIRMED' named entity 'ODDS' named entity 'ONSET' named entity '13.8' named entity 'SOUTH KOREA' named entity 'OUR' named entity 'COMPARED' named entity 'LABORATORY' named entity 'RISKS' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'MIDDLE EAST' named entity 'OLDER AGE' named entity 'CASE FATALITY RATE' named entity 'STATISTICALLY' named entity 'OUTSIDE' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'MEDIAN' named entity 'VERSION' named entity 'REPORTED' named entity 'MUCH' named entity 'COUNTRIES' named entity 'FATAL OUTCOME' named entity 'INDIVIDUALS' named entity 'RATES' named entity 'HIGHER' named entity 'CO-MORBIDITY' named entity 'DIED' named entity 'PRE-EXISTING' named entity 'CONCURRENT' named entity 'MIDDLE EAST' named entity 'CFR' named entity 'FATAL' named entity 'ISOLATED' named entity '0.003' named entity '5B1' named entity 'JUNE' named entity 'CONFIRMATION' named entity 'KOREA' named entity 'FINDINGS' named entity 'ELECTRONIC' named entity 'OUTBREAK' named entity 'SURVIVORS' named entity 'LARGEST' named entity 'INFECTED' named entity 'SUPPLEMENTARY MATERIAL' named entity 'ONLINE' named entity 'HOSPITAL' named entity 'DISEASES' named entity 'DELAYED' named entity 'OCCURRED' named entity 'CONFIRMATION OF' covid:arg/ef1524eed8ca8fad7b96301b586cafc72d15ef04

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