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About:
Dynamic causal modelling of COVID-19
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Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Dynamic causal modelling of COVID-19
Creator
Hulme, Oliver
Billig, Alexander
Daunizeau, Jean
Flandin, Guillaume
Friston, Karl
Lambert, Christian
Litvak, Vladimir
Moran, Rosalyn
Parr, Thomas
Price, Cathy
Razi, Adeel
Zeidman, Peter
Source
ArXiv
abstract
This technical report describes a dynamic causal model of the spread of coronavirus through a population. The model is based upon ensemble or population dynamics that generate outcomes, like new cases and deaths over time. The purpose of this model is to quantify the uncertainty that attends predictions of relevant outcomes. By assuming suitable conditional dependencies, one can model the effects of interventions (e.g., social distancing) and differences among populations (e.g., herd immunity) to predict what might happen in different circumstances. Technically, this model leverages state-of-the-art variational (Bayesian) model inversion and comparison procedures, originally developed to characterise the responses of neuronal ensembles to perturbations. Here, this modelling is applied to epidemiological populations to illustrate the kind of inferences that are supported and how the model per se can be optimised given timeseries data. Although the purpose of this paper is to describe a modelling protocol, the results illustrate some interesting perspectives on the current pandemic; for example, the nonlinear effects of herd immunity that speak to a self-organised mitigation process.
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2020-04-09
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arxiv
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f2b38f1b7e7ec4476ef97dc2df05a2248926828c
resource representing a document's title
Dynamic causal modelling of COVID-19
resource representing a document's body
covid:f2b38f1b7e7ec4476ef97dc2df05a2248926828c#body_text
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named entity 'EPIDEMIOLOGICAL'
named entity 'HOW'
named entity 'TIME'
named entity 'POPULATION DYNAMICS'
named entity 'MODELLING'
named entity 'model inversion'
named entity 'herd immunity'
named entity '14,000'
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named entity 'credible intervals'
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named entity 'scale parameters'
named entity 'social isolation'
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