About: Role of microbiota on lung homeostasis and diseases

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Role of microbiota on lung homeostasis and diseases
Creator	Li, F Tian, Z Wang, J
Source	PMC
abstract	The lungs, as a place of gas exchange, are continuously exposed to environmental stimuli, such as allergens, microbes, and pollutants. The development of the culture-independent technique for microbiological analysis, such as 16S rRNA sequencing, has uncovered that the lungs are not sterile and, in fact, colonized by diverse communities of microbiota. The function of intestinal microbiota in modulating mucosal homeostasis and defense has been widely studied; however, the potential function of lung microbiota in regulating immunity and homeostasis has just begun. Increasing evidence indicates the relevance of microbiota to lung homeostasis and disease. In this review, we describe the distribution and composition of microbiota in the respiratory system and discuss the potential function of lung microbiota in both health and acute/chronic lung disease. In addition, we also discuss the recent understanding of the gut-lung axis, because several studies have revealed that the immunological interaction among the gut, the lung, and the microbiota was involved in this issue.
has issue date	2017-10-09(xsd:dateTime)
bibo:doi	10.1007/s11427-017-9151-1
bibo:pmid	29019144
has license	no-cc
sha1sum (hex)	f2c0b9522fa1182a62cf2189d96205e3a93d5e89
schema:url	https://doi.org/10.1007/s11427-017-9151-1
resource representing a document's title	Role of microbiota on lung homeostasis and diseases
has PubMed Central identifier	PMC7089139
has PubMed identifier	29019144
schema:publication	Sci China Life Sci
resource representing a document's body	covid:f2c0b9522fa1182a62cf2189d96205e3a93d5e89#body_text
is schema:about of	named entity 'composition' named entity 'homeostasis' named entity 'lungs' named entity 'respiratory system' named entity 'exposed' named entity 'DEVELOPMENT' named entity 'PLACE' named entity 'LUNG DISEASE' named entity 'HOMEOSTASIS' named entity 'POLLUTANTS' named entity 'EXPOSED TO' named entity 'ALLERGENS' named entity 'REGULATING' named entity 'GAS EXCHANGE' named entity 'STUDIES' named entity 'MICROBES' named entity 'FACT' named entity 'COMMUNITIES' named entity 'CULTURE-INDEPENDENT' named entity 'INTERACTION' named entity 'HAVE' named entity 'ROLE' named entity 'MICROBIOTA' named entity 'LUNG' named entity 'DISEASES' named entity 'HOMEOSTASIS' named entity 'RESPIRATORY SYSTEM' named entity 'LUNG' named entity 'THE GUT' named entity 'THE LUNGS' named entity 'RELEVANCE' named entity 'INVOLVED' named entity 'MICROBIOLOGICAL ANALYSIS' named entity 'EVIDENCE' named entity 'DIVERSE' named entity 'INTESTINAL MICROBIOTA' named entity 'UNDERSTANDING' named entity 'POTENTIAL' named entity 'DEFENSE' named entity 'AXIS' named entity 'ADDITION' named entity 'HEALTH' named entity 'ACUTE' named entity 'DESCRIBE' named entity 'MODULATING' named entity 'MICROBIOTA' named entity 'FUNCTION' named entity 'ENVIRONMENTAL STIMULI' named entity 'REVIEW' named entity 'REVEALED' named entity 'IMMUNOLOGICAL' named entity 'IMMUNITY' named entity 'COMPOSITION' named entity 'ISSUE' named entity 'DISCUSS' named entity 'RECENT' named entity 'STERILE' named entity 'MUCOSAL' named entity 'INCREASING' named entity 'UNCOVERED' named entity 'DISTRIBUTION' named entity 'JUST' named entity 'DISEASE' named entity 'TECHNIQUE' named entity 'homeostasis' named entity 'health' named entity 'microbiota' named entity 'studied' named entity 'microbiota' named entity 'microbiota' named entity 'distribution' named entity '16S rRNA' named entity 'lung' named entity 'microbiota' named entity 'environmental stimuli' named entity 'microbiota' named entity 'homeostasis' named entity 'microbiota' named entity 'lung disease'

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