About: Triterpenoids from the stems of Tripterygium regelii

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About: Triterpenoids from the stems of Tripterygium regelii Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Triterpenoids from the stems of Tripterygium regelii
Creator	Bai, Li-Ping Fan, Dongsheng Jiang, Zhi-Hong Parhira, Supawadee Zhu, Guo-Yuan
Source	Elsevier; Medline; PMC
abstract	Abstract Three new triterpenoids, triregelolides A, B (1, 2), and triregeloic acid (3), were isolated from the stems of Tripterygium regelii along with twenty known triterpene analogues (4–23). The structures of three new compounds were identified by analyzing their NMR spectroscopic and HRESIMS data. Compounds 4, 7, 8, 10, 13, 14, 17, 21–23 were isolated from T. regelii for the first time. Compounds 3, 5, 6, 8, 9, 10, 14 and 16 showed inhibitory effects on the proliferation of human breast cancer cells MCF-7 by 24.1%, 69.6%, 72.8%, 21.6%, 23.1%, 43.3%, 25.5% and 23.5% (p <0.05) at a concentration of 10μM, respectively.
has issue date	2016-09-30(xsd:dateTime)
bibo:doi	10.1016/j.fitote.2016.07.006
bibo:pmid	27425447
has license	els-covid
sha1sum (hex)	f320d203300637482f2e07d2f41f7cacc3df6252
schema:url	https://doi.org/10.1016/j.fitote.2016.07.006
resource representing a document's title	Triterpenoids from the stems of Tripterygium regelii
has PubMed Central identifier	PMC7126508
has PubMed identifier	27425447
schema:publication	Fitoterapia
resource representing a document's body	covid:f320d203300637482f2e07d2f41f7cacc3df6252#body_text
is schema:about of	named entity 'CID' named entity 'acid' named entity 'PubChem' named entity 'CID' named entity 'TRITERPENOIDS' named entity '10%' named entity 'CHEMICAL COMPOUNDS' named entity 'REGELINOL' named entity 'POLPUNONIC ACID' named entity 'TRIPTERYGIC ACID A' named entity 'CELASTROL' named entity 'DEMETHYLZEYLASTERAL' named entity 'WILFOROL A' named entity '158' named entity '129' named entity 'CID' named entity '101' named entity 'ARTICLE' named entity '174' named entity 'ACID' named entity 'REGELIN D' named entity 'WILFORLIDE B' named entity 'STEMS' named entity 'TRIPTERYGIUM REGELII' named entity 'REGELIN' named entity 'WILFORLIDE A' named entity 'TRIPTOTRITERPENIC ACID B' named entity '163' named entity '195' covid:arg/f320d203300637482f2e07d2f41f7cacc3df6252 named entity 'PubChem' named entity 'PubChem' named entity 'PubChem' named entity 'PubChem CID' named entity 'PubChem CID' named entity 'PubChem CID' named entity 'PubChem CID' named entity 'Chemical compounds' named entity 'PubChem CID' named entity 'quaternary' named entity 'TLC' named entity 'tetramethylsilane' named entity '37°C' named entity 'methoxy' named entity 'terpenoids' named entity 'quaternary' named entity 'esterified' named entity 'TLC' named entity 'antitumor' named entity 'methyl' named entity 'ketal' named entity 'hydroxyl group' named entity 'absorbance' named entity 'coupling constant' named entity 'TLC' named entity 'unsaturated' named entity 'phytochemical' named entity 'SARS' named entity 'culture medium' named entity 'triterpene' named entity 'lysing' named entity 'HMBC' named entity 'Invitrogen' named entity 'biological activities' named entity 'neuroprotective effects' named entity 'C-29' named entity 'methylenes' named entity 'methoxyl' named entity 'room temperature' named entity 'solvent' named entity 'microplate reader' named entity 'DMEM' named entity 'hepatoprotective' named entity 'MCF-7' named entity 'electrospray ionization' named entity 'MCF-7 cells' named entity 'triterpenoids'

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