About: Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers
Creator	Rello, Jordi Belliato, Mirko Storti, Enrico Serrano, Ricardo
Source	Medline; PMC
abstract	Patients with COVID-19 present a broad spectrum of clinical presentation. Whereas hypoxaemia is the marker of severity, different strategies of management should be customised to five specific individual phenotypes. Many intubated patients present with phenotype 4, characterised by pulmonary hypoxic vasoconstriction, being associated with severe hypoxaemia with “normal” (>40 mL·cmH(2)O(−1)) lung compliance and likely representing pulmonary microvascular thrombosis. Phenotype 5 is often associated with high plasma procalcitonin and has low pulmonary compliance, Which is a result of co-infection or acute lung injury after noninvasive ventilation. Identifying these clinical phenotypes and applying a personalised approach would benefit the optimisation of therapies and improve outcomes.
has issue date	2020-05-21(xsd:dateTime)
bibo:doi	10.1183/13993003.01028-2020
bibo:pmid	32341111
has license	cc-by-nc
sha1sum (hex)	f483d6b3c3ee441bd180f37a5815935881301fee
schema:url	https://doi.org/10.1183/13993003.01028-2020
resource representing a document's title	Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers
has PubMed Central identifier	PMC7236837
has PubMed identifier	32341111
schema:publication	Eur Respir J
resource representing a document's body	covid:f483d6b3c3ee441bd180f37a5815935881301fee#body_text
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