About: Clinical characteristics of acute respiratory syndrome with SARS‐CoV‐2 infection in children in South China

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About: Clinical characteristics of acute respiratory syndrome with SARS‐CoV‐2 infection in children in South China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics of acute respiratory syndrome with SARS‐CoV‐2 infection in children in South China
Creator	Zhu, Hong Meng, Qiong Zhang, Hua Zhang, Yuehua Wang, Bangqin Xie, \| Gao, Wenjun Guo, Qingyun Guo, Yuxiong Jiang, Suhua Liang, Jiayi Liu, Guojun Wang, Yanhao Xie, Chuxing Ye, Guojing Zheng, Guilang Zhihong, \|
Source	Medline; PMC
abstract	BACKGROUND: A retrospective study was conducted to summarize the clinical information of childhood infections during the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) epidemic. METHODS: Children with SARS‐CoV‐2 infection in 11 hospitals from three provinces of South China were included in the study. Clinical information was collected and compared with children and adults infected by SARS‐CoV‐2 in Wuhan. RESULTS: In total, 52 children were enrolled, including 28 boys. The median age was 9 years (interquartile range [IQR], 4‐12); 44.2% cases were of clustered occurrences, 40.4% patients had fever, 48.1% had cough, and 46.2% had a high lymphocyte count. No abnormalities were found in the liver and kidney function. Also, 82.7% of patients received antiviral therapy, but such therapy did not shorten the time to virus negativity or hospital stay (P = .082). The time to virus negativity was 12.0 days (IQR, 8.0‐16.8) and hospital stay was 14.5 days (IQR, 10.3‐17.9). Compared with reports in Wuhan, there were more acute upper respiratory tract infection (AURTI) and fewer pneumonia cases (P = .000). Compared with the non‐ICU adult COVID‐19 in Wuhan, these children's diseases were relatively mild, with fewer complications. CONCLUSIONS: Children with SARS‐CoV‐2 infection had a mild fever, lymphocyte elevation was more common than reduction, and antiviral treatment had no obvious effect. The overall clinical manifestations were mild, and the prognosis was good.
has issue date	2020-07-03(xsd:dateTime)
bibo:doi	10.1002/ppul.24921
bibo:pmid	32579293
has license	no-cc
sha1sum (hex)	f4a64fd960f4367f46b81c71a50686518a110da8
schema:url	https://doi.org/10.1002/ppul.24921
resource representing a document's title	Clinical characteristics of acute respiratory syndrome with SARS‐CoV‐2 infection in children in South China
has PubMed Central identifier	PMC7361845
has PubMed identifier	32579293
schema:publication	Pediatr Pulmonol
resource representing a document's body	covid:f4a64fd960f4367f46b81c71a50686518a110da8#body_text
is schema:about of	named entity 'infection' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2' covid:arg/f4a64fd960f4367f46b81c71a50686518a110da8 named entity 'infections' named entity 'retrospective study' named entity 'epidemic' named entity 'respiratory failure' named entity 'shortness of breath' named entity 'one-way analysis of variance' named entity 'sore throat' named entity 'fever' named entity 'ARDS' named entity 'arbidol' named entity 'prognosis' named entity 'lymphocyte count' named entity 'epidemic' named entity 'patients' medical records' named entity 'upper respiratory tract infection' named entity 'SARS-CoV-2' named entity 'steroids' named entity 'leukocyte' named entity 'SARS-CoV-2' named entity 'immune dysfunction' named entity 'SPSS' named entity 'interquartile range' named entity 'pediatric' named entity 'lopinavir/ritonavir' named entity 'human interferon' named entity 'coagulation' named entity 'pediatric' named entity 'acute respiratory distress syndrome' named entity 'shortness of breath' named entity 'cyanosis' named entity 'fever' named entity 'SARS-CoV-2' named entity 'significant effect' named entity 'lopinavir/ritonavir' named entity '0.9' named entity 'antiviral drugs' named entity 'clinical data' named entity 'headache' named entity 'Social Sciences' named entity 'symptoms and signs' named entity 'liver' named entity 'epidemiological' named entity '1, 2' named entity 'Epidemiologic data' named entity 'interquartile range' named entity 'Wuhan' named entity '1.2' named entity 'Wuhan' named entity 'respiratory complications' named entity 'SARS-CoV-2' named entity 'leukocyte count' named entity 'Ribavirin' named entity 'Wilcoxon signed rank test' named entity 'COVID' named entity 'China' named entity 'clinical treatment' named entity 'SPSS' named entity 'antiviral drugs' named entity 'gastrointestinal symptoms' named entity 'respiratory droplets' named entity 'pneumonia' named entity 'virus'

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