About: Detection and analysis of clinical features of patients with different COVID‐19 types

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About: Detection and analysis of clinical features of patients with different COVID‐19 types Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Detection and analysis of clinical features of patients with different COVID‐19 types
Creator	Huang, He Zhou, Jie Wu, Wei Chen, Jun Zhao, Yi Wang, Honggang He, Jingsong Pan, Liuhua Zhang, Yujie
Source	Medline; PMC
abstract	OBJECTIVE: This study was designed to investigate the change of various indexes in patients with different types of coronavirus disease 2019 (COVID‐19). METHODS: 75 COVID‐19 patients were collected from the First Affiliated Hospital, Zhejiang University School of Medicine, and they were classified into moderate, severe and critically severe types according to the disease severity. The basic information, blood routine, pneumonia‐related blood indexes, immune‐related indexes along with liver, kidney and myocardial indexes in patients with different types were analyzed. RESULTS: The analysis of immune‐related indexes showed that the proportions of critically severe patients with abnormal IL‐2 and IL‐4 were higher than those of severe and moderate patients. In addition, the proportion of patients with abnormal total cholesterol increased as the severity of disease increased, and the proportion in critically severe patients was significantly higher than that in moderate patients. CONCLUSIONS: The patients with a more severe COVID‐19 are older and more likely to have a history of hypertension. With the progression of COVID‐19, the abnormal proportion of total white blood cell, neutrophils, lymphocytes, IL‐2, IL‐4 and total cholesterol increased. The change of these indexes in patients with different COVID‐19 types could provide reference for the disease severity identification and diagnosis of COVID‐19. In addition, the change in the total cholesterol level suggested that COVID‐19 would induce some liver function damage in patients. This article is protected by copyright. All rights reserved.
has issue date	2020-06-26(xsd:dateTime)
bibo:doi	10.1002/jmv.26225
bibo:pmid	32589755
has license	no-cc
sha1sum (hex)	f673dc1b40947d0db162e1c9e84b188bba21e33f
schema:url	https://doi.org/10.1002/jmv.26225
resource representing a document's title	Detection and analysis of clinical features of patients with different COVID‐19 types
has PubMed Central identifier	PMC7361356
has PubMed identifier	32589755
schema:publication	J Med Virol
resource representing a document's body	covid:f673dc1b40947d0db162e1c9e84b188bba21e33f#body_text
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