About: The First Consecutive 5000 Patients with Coronavirus Disease 2019 from Qatar; a Nation-wide Cohort Study

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The First Consecutive 5000 Patients with Coronavirus Disease 2019 from Qatar; a Nation-wide Cohort Study
Creator	Al Khal, Abdullatif Coyle, Peter Omrani, Ali Abid, Fatma Hssain, Ali Abdalla, Shiema Akkari, Abdelrauof Badawi, Mohamed Bakdach, Dana Bertollini, Roberto Abukhattab, Mohammed Al-Ismail, Khalil Alattar, Rand Alhariri, Bassem Alkawari, Hanan Almaslamani, Muna Baiou, Anas Chinta, Venkateswara Choda, Kris Daghfal, Joanne Elajez, Reem Elgara, Mohamed Frenneaux, Michael Husain, Ahmed Ibrahim, Tawheeda Jarir, Sulieman Kaleeckal, Anvar Shaar, Shahd Sherbash, Mohamed Zaqout, Ahmed
Source	MedRxiv
abstract	Background There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-day all-cause mortality associated with COVID-19, and to identify risk factors associated with admission to an intensive care unit (ICU). Methods This was a retrospective cohort study including the first consecutive 5000 patients with COVID-19 in Qatar who completed 60 days of follow up by June 17, 2020. Outcomes included all-cause mortality at 60 days after COVID-19 diagnosis, and risk factors for admission to ICU. Results Included patients were diagnosed with COVID-19 between February 28 and April 17, 2020. The majority (4436, 88.7%) were males and the median age was 35 years [interquartile range (IQR) 28-43]. By 60 days after COVID-19 diagnosis, 14 patients (0.28%) had died, 10 (0.2%) were still in hospital, and two (0.04%) were still in ICU. Fatal COVID-19 cases had a median age of 59.5 years (IQR 55.8-68), and were mostly males (13, 92.9%). All included pregnant women (26, 0.5%), children (131, 2.6%), and healthcare workers (135, 2.7%) were alive and not hospitalized at the end of follow up. A total of 1424 patients (28.5%) required hospitalization, out of which 108 (7.6%) were admitted to ICU. Most frequent co-morbidities in hospitalized adults were diabetes (23.2%), and hypertension (20.7%). Multivariable logistic regression showed that older age [adjusted odds ratio (aOR) 1.041, 95% confidence interval (CI) 1.022-1.061 per year increase; P <0.001], male sex (aOR 4.375, 95% CI 1.964-9.744; P <0.001), diabetes (aOR 1.698, 95% CI 1.050-2.746; P 0.031), chronic kidney disease (aOR 3.590, 95% CI 1.596-8.079, P 0.002), and higher BMI (aOR 1.067, 95% CI 1.027-1.108 per unit increase; P 0.001), were all independently associated with increased risk of ICU admission. Conclusions In a relatively younger national cohort with a low co-morbidity burden, COVID-19 was associated with low all-cause mortality. Independent risk factors for ICU admission included older age, male sex, higher BMI, and co-existing diabetes or chronic kidney disease.
has issue date	2020-07-16(xsd:dateTime)
bibo:doi	10.1101/2020.07.15.20154690
has license	medrxiv
sha1sum (hex)	f6e0433a4b89539165f817c99f6e7d6e2a97f0d5
schema:url	https://doi.org/10.1101/2020.07.15.20154690
resource representing a document's title	The First Consecutive 5000 Patients with Coronavirus Disease 2019 from Qatar; a Nation-wide Cohort Study
resource representing a document's body	covid:f6e0433a4b89539165f817c99f6e7d6e2a97f0d5#body_text
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