About: Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases

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About: Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases
Creator	Moise, Leonard Pilotte, Nils Torres, Melissa Martin, Rebecca De Groot, Anne Terry, Frances Williams, Steven
topic	covid:f71c5fc3040dbc1fa7419bf6004a53353f32590b#this
Source	Medline; PMC
abstract	Vaccines have been invaluable for global health, saving lives and reducing healthcare costs, while also raising the quality of human life. However, newly emerging infectious diseases (EID) and more well-established tropical disease pathogens present complex challenges to vaccine developers; in particular, neglected tropical diseases, which are most prevalent among the world’s poorest, include many pathogens with large sizes, multistage life cycles and a variety of nonhuman vectors. EID such as MERS-CoV and H7N9 are highly pathogenic for humans. For many of these pathogens, while their genomes are available, immune correlates of protection are currently unknown. These complexities make developing vaccines for EID and neglected tropical diseases all the more difficult. In this review, we describe the implementation of an immunoinformatics-driven approach to systematically search for key determinants of immunity in newly available genome sequence data and design vaccines. This approach holds promise for the development of 21st century vaccines, improving human health everywhere.
has issue date	2015-01-02(xsd:dateTime)
bibo:doi	10.1586/14760584.2015.955478
bibo:pmid	25193104
has license	no-cc
sha1sum (hex)	f71c5fc3040dbc1fa7419bf6004a53353f32590b
schema:url	https://doi.org/10.1586/14760584.2015.955478
resource representing a document's title	Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases
has PubMed Central identifier	PMC4743591
has PubMed identifier	25193104
schema:publication	Expert Rev Vaccines
resource representing a document's body	covid:f71c5fc3040dbc1fa7419bf6004a53353f32590b#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/f71c5fc3040dbc1fa7419bf6004a53353f32590b
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