About: Preventing respiratory syncytial virus infections in hospitalized children and adults: should we do better?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Preventing respiratory syncytial virus infections in hospitalized children and adults: should we do better?
Creator	Scemla, Anne Frange, Pierre Leruez-Ville, Marianne Moulin, Florence Parize, Perrine Toubiana, Julie
Source	Elsevier; PMC
abstract	Summary Objective To compare the burden of nosocomial and community-acquired respiratory syncytial virus (RSV)-associated acute lower respiratory tract infections (ALRIs) in adult and pediatric patients concomitantly admitted to a French tertiary hospital, and to evaluate the effectiveness of existing infection control measures. Patients and methods We prospectively included all adult and pediatric patients admitted to Necker hospital (Paris) between October 2018 and February 2019 with a diagnosis of RSV-associated ALRI. We compared characteristics of ALRIs between patients with community-acquired versus nosocomial infections and, in each group, between children and adults. Results Community-acquired and nosocomial RSV-associated ALRIs were diagnosed in 229 and 11 inpatients, respectively. The burden of community-acquired infections was higher in children than in adults: 2.1% versus 0.2% of the total number of pediatric and adult inpatients, respectively (p < 0.0001); 4.2% versus 0.2% of the total number of hospitalization days in pediatric and adult units, respectively (p < 0.0001). Compared to inpatients with community-acquired ALRIs, those with nosocomial infections were more frequently adults (45.5% versus 2.6%, p = 0.0005) and subjects with at least one chronic complex condition (100.0% versus 41.0%, p < 0.0001). The total number of hospitalization days due to nosocomial ALRIs was higher in adults than in children (0.32% versus 0.11%, p < 0.0001). Conclusions Nosocomial RSV-associated ALRIs rarely occurred, suggesting a good effectiveness of our infection control strategy. However, the burden of nosocomial infection was higher in adults than in children, suggesting that education and training of healthcare personnel, patients and visitors about the risk of nosocomial RSV infections should be reinforced in adult wards.
has issue date	2020-06-30(xsd:dateTime)
bibo:doi	10.1016/j.infpip.2020.100041
has license	els-covid
sha1sum (hex)	f738928dba37be9b02edcdaf480cc8c653614585
schema:url	https://doi.org/10.1016/j.infpip.2020.100041
resource representing a document's title	Preventing respiratory syncytial virus infections in hospitalized children and adults: should we do better?
has PubMed Central identifier	PMC7148660
schema:publication	Infection Prevention in Practice
resource representing a document's body	covid:f738928dba37be9b02edcdaf480cc8c653614585#body_text
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