About: Diagnostic Testing or Empirical Therapy for Patients Hospitalized with Suspected Influenza: What to Do?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diagnostic Testing or Empirical Therapy for Patients Hospitalized with Suspected Influenza: What to Do?
Creator	Mcgeer, Allison
Source	Medline; PMC
abstract	Accumulating evidence supports the use of specific diagnostic tests and antiviral therapies for seriously ill patients with influenza. Among available diagnostic tests, reverse-transcriptase polymerase chain reaction is faster than culture and more sensitive than commercial antigen assays. Current neuraminidase inhibitors were approved on the basis of their efficacy in ambulatory patients, but seriously ill patients who receive these agents are less likely to die, even when treatment is initiated >48 h after symptom onset. For patients hospitalized with suspected influenza, it is unclear which circumstances warrant diagnostic testing and which warrant the use of empirical therapy. Rapid antigen assays may reduce the unnecessary use of other tests and medications but are relatively insensitive, thus eliminating many patients with influenza as candidates for treatment. Empirical antiviral therapy ensures that all patients receive treatment promptly, at a cost equivalent to that of diagnostic tests alone, but results in the receipt of treatment by many patients without influenza. For patients hospitalized with suspected influenza, clinicians need to combine these approaches in order to optimize patient care.
has issue date	2009-01-01(xsd:dateTime)
bibo:doi	10.1086/591852
bibo:pmid	19067610
has license	no-cc
sha1sum (hex)	f7770c4c37da65904e2371457661b1927eac9a67
schema:url	https://doi.org/10.1086/591852
resource representing a document's title	Diagnostic Testing or Empirical Therapy for Patients Hospitalized with Suspected Influenza: What to Do?
has PubMed Central identifier	PMC7107924
has PubMed identifier	19067610
schema:publication	Clin Infect Dis
resource representing a document's body	covid:f7770c4c37da65904e2371457661b1927eac9a67#body_text
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