About: Intermediate conformations during viral fusion glycoprotein structural transition

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Intermediate conformations during viral fusion glycoprotein structural transition
Creator	Lepault, Jean Gaudin, Yves Baquero, Eduard Sté Phane Bressanelli, Vachette, Patrice Albertini, A Auré,
source	Elsevier; Medline; PMC
abstract	Entry of enveloped viruses into cells requires the fusion of viral and cellular membranes, driven by conformational changes in viral glycoproteins. Three different classes of viral fusion proteins have been hitherto identified based on common structural elements. Crystal structures have provided static pictures of pre-fusion and post-fusion conformations of these proteins and have revealed the dramatic reorganization of the molecules, but the transition pathway remains elusive. In this review, we will focus on recent data aiming to characterize intermediate structures during the conformational change. All these data support the existence of a pre-hairpin intermediate, but its oligomeric status is still a matter of debate.
has issue date	2013-04-30(xsd:dateTime)
bibo:doi	10.1016/j.coviro.2013.03.006
bibo:pmid	23562213
has license	els-covid
sha1sum (hex)	f8360194e4695b4882c1b0bce6b467fb86e57516
schema:url	https://doi.org/10.1016/j.coviro.2013.03.006
resource representing a document's title	Intermediate conformations during viral fusion glycoprotein structural transition
has PubMed Central identifier	PMC7172239
has PubMed identifier	23562213
schema:publication	Current Opinion in Virology
resource representing a document's body	covid:f8360194e4695b4882c1b0bce6b467fb86e57516#body_text
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