About: Effect of oxygenation modalities among patients with postoperative respiratory failure: a pairwise and network meta-analysis of randomized controlled trials

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About: Effect of oxygenation modalities among patients with postoperative respiratory failure: a pairwise and network meta-analysis of randomized controlled trials Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Effect of oxygenation modalities among patients with postoperative respiratory failure: a pairwise and network meta-analysis of randomized controlled trials
Creator	Bachuwa, Ghassan Bala, Areeg Barbarawi, Mahmoud Kerbage, Josiane Rizk, Fatima Seedahmed, Elfateh Zayed, Yazan Esra'a Ismail, Gakhal, Inderdeep Kheiri, Babikir Rashdan, Laith Shafi, Saadia Sidahmed, Shima
source	PMC
abstract	BACKGROUND: Postoperative respiratory failure is associated with increased perioperative complications. Our aim is to compare outcomes between non-invasive ventilation (NIV), high-flow nasal cannula (HFNC), and standard oxygen in patients at high-risk for or with established postoperative respiratory failure. METHODS: Electronic databases including PubMed, Embase, and the Cochrane Library were reviewed from inception to September 2019. We included only randomized controlled trials (RCTs) that compared NIV, HFNC, and standard oxygen in patients at high risk for or with established postoperative respiratory failure. We performed a Bayesian network meta-analysis to calculate the odds ratio (OR) and Bayesian 95% credible intervals (CrIs). RESULTS: Nine RCTs representing 1865 patients were included (the mean age was 61.6 ± 10.2 and 64.4% were males). In comparison with standard oxygen, NIV was associated with a significant reduction in intubation rate (OR 0.23; 95% Cr.I. 0.10–0.46), mortality (OR 0.45; 95% Cr.I. 0.27–0.71), and intensive care unit (ICU)-acquired infections (OR 0.43, 95% Cr.I. 0.25–0.70). Compared to standard oxygen, HFNC was associated with a significant reduction in intubation rate (OR 0.28, 95% Cr.I. 0.08–0.76) and ICU-acquired infections (OR 0.41; 95% Cr.I. 0.20–0.80), but not mortality (OR 0.58; 95% Cr.I. 0.26–1.22). There were no significant differences between HFNC and NIV regarding different outcomes. In a subgroup analysis, we observed a mortality benefit with NIV over standard oxygen in patients undergoing cardiothoracic surgeries but not in abdominal surgeries. Furthermore, in comparison with standard oxygen, NIV and HFNC were associated with lower intubation rates following cardiothoracic surgeries while only NIV reduced the intubation rates following abdominal surgeries. CONCLUSIONS: Among patients with post-operative respiratory failure, HFNC and NIV were associated with significantly reduced rates of intubation and ICU-acquired infections compared with standard oxygen. Moreover, NIV was associated with reduced mortality in comparison with standard oxygen.
has issue date	2020-07-17(xsd:dateTime)
bibo:doi	10.1186/s40560-020-00468-x
has license	cc-by
sha1sum (hex)	f88871df0a693a08a015a36561b141e344e615df
schema:url	https://doi.org/10.1186/s40560-020-00468-x
resource representing a document's title	Effect of oxygenation modalities among patients with postoperative respiratory failure: a pairwise and network meta-analysis of randomized controlled trials
has PubMed Central identifier	PMC7366473
schema:publication	J Intensive Care
resource representing a document's body	covid:f88871df0a693a08a015a36561b141e344e615df#body_text
is schema:about of	named entity 'Our' named entity 'NIV' named entity 'Cochrane Library' named entity 'Electronic' named entity 'aim' named entity 'patients' named entity 'NASAL CANNULA' named entity 'INCLUDING' named entity 'INCREASED' named entity 'DIFFERENT' named entity '0.45' named entity '2019' named entity 'performed' named entity 'reduced' named entity 'NIV' named entity 'intubation' named entity 'reduced' named entity 'high risk' named entity 'patients' named entity 'respiratory failure' named entity 'perioperative' named entity 'respiratory failure' named entity 'compared' named entity 'compare' named entity 'intubation' named entity 'meta-' named entity 'oxygen' named entity '95%' named entity 'intubation' named entity 'high-risk' named entity 'HFNC' named entity 'September 2019' named entity 'respiratory failure' named entity 'oxygen' named entity 'intensive care unit' named entity 'oxygen' named entity 'nasal cannula' named entity 'credible intervals' named entity 'odds ratio' named entity 'NIV' named entity 'oxygenation' named entity 'NIV' named entity 'catheter-associated' named entity 'mortality rates' named entity 'network meta-analysis' named entity 'respiratory failure' named entity 'intubation' named entity 'cardiac dysfunction' named entity 'oxygen' named entity 'beta distribution' named entity 'NIV' named entity 'oxygen' named entity 'oxygen therapy' named entity 'meta-analysis' named entity 'hypoxemic' named entity 'NIV' named entity 'significant difference' named entity 'RCTs' named entity 'Sensitivity analysis' named entity 'oxygen therapy' named entity 'oxygen therapy' named entity 'HFNC' named entity 'lung' named entity 'abdominal surgery' named entity 'NIV' named entity 'positive pressure' named entity 'Physiology' named entity 'pulmonary complications' named entity 'NIV' named entity 'posterior distribution' named entity 'intubation'

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