About: Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection
Creator	Zhang, Cheng Li, Yan Zhao, Lei Hammerschmidt, Sven Li, Zhao Bao, Lirong Dong, Jiajia Saliba, Antoine-Emmanuel Sun, Jianxun Karygianni, Lamprini
topic	covid:f8ec3f6fc8eb2a92bc62f5f70482571f7a39a1b1#this
Source	Medline; PMC
abstract	The new coronavirus SARS-CoV-2, the cause of COVID-19, has become a public health emergency of global concern. Like the SARS and influenza pandemics, there have been a large number of cases coinfected with other viruses, fungi, and bacteria, some of which originate from the oral cavity. Capnocytophaga, Veillonella, and other oral opportunistic pathogens were found in the BALF of the COVID-19 patients by mNGS. Risk factors such as poor oral hygiene, cough, increased inhalation under normal or abnormal conditions, and mechanical ventilation provide a pathway for oral microorganisms to enter the lower respiratory tract and thus cause respiratory disease. Lung hypoxia, typical symptoms of COVID-19, would favor the growth of anaerobes and facultative anaerobes originating from the oral microbiota. SARS-CoV-2 may aggravate lung disease by interacting with the lung or oral microbiota via mechanisms involving changes in cytokines, T cell responses, and the effects of host conditions such as aging and the oral microbiome changes due to systemic diseases. Because the oral microbiome is closely associated with SARS-CoV-2 co-infections in the lungs, effective oral health care measures are necessary to reduce these infections, especially in severe COVID-19 patients. We hope this review will draw attention from both the scientific and clinical communities on the role of the oral microbiome in the current global pandemic.
has issue date	2020-07-31(xsd:dateTime)
bibo:doi	10.3389/fmicb.2020.01840
bibo:pmid	32849438
has license	cc-by
sha1sum (hex)	f8ec3f6fc8eb2a92bc62f5f70482571f7a39a1b1
schema:url	https://doi.org/10.3389/fmicb.2020.01840
resource representing a document's title	Oral Microbiome and SARS-CoV-2: Beware of Lung Co-infection
has PubMed Central identifier	PMC7411080
has PubMed identifier	32849438
schema:publication	Front Microbiol
resource representing a document's body	covid:f8ec3f6fc8eb2a92bc62f5f70482571f7a39a1b1#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/f8ec3f6fc8eb2a92bc62f5f70482571f7a39a1b1
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