About: Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study

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About: Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study
Creator	Xiong, Yong Chen, Tielong Chen, Xiaoping Deng, Liping Gao, Shicheng Liang, Ke Luo, Mingqi Ma, Zhiyong Mo, Pingzheng Song, Shihui Zhang, Yongxi Li, Xinyu Dai, Zhe
Source	Medline; PMC
abstract	BACKGROUND: In December 2019, the coronavirus disease 2019 (COVID-19) emerged in Wuhan city and spread rapidly throughout China and the world. In this study, we aimed to describe the clinical course and outcomes of older patients with COVID-19. METHODS: This is a retrospective investigation of hospitalized older patients with confirmed COVID-19 at Zhongnan Hospital of Wuhan University from January 1, 2020, to February 10, 2020. RESULTS: In total, 203 patients were diagnosed with COVID-19, with a median age of 54 years (interquartile range, 41-68; range, 20-91 years). Men accounted for 108 (53.2%) of the cases, and 55 patients (27.1%) were >65 years of age. Among patients who were 65 years and older, the mortality rate was 34.5% (19/55), which was significantly higher than that of younger patients at 4.7% (7/148). Common symptoms of older patients with COVID-19 included fever (94.5%; n=52), dry cough (69.1%; n=38), and chest distress (63.6%; n=35). Compared with young patients, older patients had more laboratory abnormalities and comorbidities. Through a multivariate analysis of the causes of death in older patients, we found that males, comorbidities, time from disease onset to hospitalization, abnormal kidney function, and elevated procalcitonin levels were all significantly associated with death. CONCLUSIONS: In the recent outbreak of COVID-19, our local hospital in Wuhan found that patients aged 65 and older had greater initial comorbidities, more severe symptoms, and were more likely to experience multi-organ involvement and death, as compared with younger patients.
has issue date	2020-04-11(xsd:dateTime)
bibo:doi	10.1093/gerona/glaa089
bibo:pmid	32279081
has license	no-cc
sha1sum (hex)	f9a18334e2c1e7eca6cedf5ccd0abfbdfcaa8187
schema:url	https://doi.org/10.1093/gerona/glaa089
resource representing a document's title	Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study
has PubMed Central identifier	PMC7184388
has PubMed identifier	32279081
schema:publication	J Gerontol A Biol Sci Med Sci
resource representing a document's body	covid:f9a18334e2c1e7eca6cedf5ccd0abfbdfcaa8187#body_text
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