About: Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials

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About: Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials
Creator	Kirby, James Dale, Alana Green, Alex Jagdish, Tanush Nguyen Ba, Alex Reif, Dvir Seeley, Robert Zulauf, Katelyn
Source	MedRxiv; Medline; PMC
abstract	The SARS-CoV-2 pandemic has caused a severe, international shortage of N95 respirators, which are essential to protect healthcare providers from infection. Given the contemporary limitations of the supply chain, it is imperative to identify effective means of decontaminating, reusing, and thereby conserving N95 respirator stockpiles. To be effective, decontamination must result in sterilization of the N95 respirator without impairment of respirator filtration or user fit. Although numerous methods of N95 decontamination exist, none are universally accessible. In this work we describe a microwave-generated steam decontamination protocol for N95 respirators for use in health care systems of all sizes, geographies, and means. Using widely available glass containers, mesh from commercial produce bags, a rubber band, and a 1100W commercially available microwave, we constructed an effective, standardized, and reproducible means of decontaminating N95 respirators. Employing this methodology against MS2 phage, a highly conservative surrogate for SARS-CoV-2 contamination, we report an average 6-log(10) plaque forming unit (PFU) (99.9999%) and a minimum 5-log(10) PFU (99.999%) reduction after a single three-minute microwave treatment. Notably, quantified respirator fit and function were preserved, even after 20 sequential cycles of microwave steam decontamination. This method provides a valuable means of effective decontamination and reuse of N95 respirators by frontline providers facing urgent need.
has issue date	2020-04-25(xsd:dateTime)
bibo:doi	10.1101/2020.04.22.20076117
bibo:pmid	32511577
has license	cc-by-nc-nd
sha1sum (hex)	fa003e3fc6af66be5abc79ddb560f2a57785e4e6
schema:url	https://doi.org/10.1101/2020.04.22.20076117
resource representing a document's title	Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials
has PubMed Central identifier	PMC7276004
has PubMed identifier	32511577
schema:publication	medRxiv
resource representing a document's body	covid:fa003e3fc6af66be5abc79ddb560f2a57785e4e6#body_text
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