About: Symptoms of COVID-19 Outpatients in the United States

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Symptoms of COVID-19 Outpatients in the United States
Creator	Abassi, Mahsa Bangdiwala, Ananta Boulware, David Engen, Nicole Galdys, Alison Hullsiek, Kathy Lofgren, Sarah Okafor, Elizabeth Pastick, Katelyn Pullen, Matthew Rajasingham, Radha Skipper, Caleb Williams, Darlisha
Source	PMC
abstract	BACKGROUND: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel pathogen causing the current worldwide coronavirus disease 2019 (COVID-19) pandemic. Due to insufficient diagnostic testing in the United States, there is a need for clinical decision-making algorithms to guide testing prioritization. METHODS: We recruited participants nationwide for a randomized clinical trial. We categorized participants into three groups: 1) those with confirmed SARS-CoV-2 infection, 2) those with probable SARS-CoV-2 infection (pending test or not tested but with a confirmed COVID-19 contact), and 3) those with possible SARS-CoV-2 infection (pending test or not tested and with a contact for whom testing was pending or not performed). We compared the frequency of self-reported symptoms in each group and categorized those reporting symptoms in early infection (0 – 2 days), mid-infection (3 – 5 days), and late infection (>5 days). RESULTS: Among 1,252 symptomatic persons screened, 316 had confirmed, 393 had probable, and 543 had possible SARS-CoV-2 infection. In early infection, those with confirmed and probable SARS-CoV-2 infection shared similar symptom profiles, with fever most likely in confirmed cases (p = 0.002). Confirmed cases did not show any statistically significant differences compared to unconfirmed cases in symptom frequency at any time points. The most commonly reported symptoms in those with confirmed infection were cough (82%), fever (67%), fatigue (62%), and headache (60%), with only 52% reporting both fever and cough. CONCLUSION: Symptomatic persons with probable SARS-CoV-2 infection present similarly to those with confirmed SARS-CoV-2 infection. There was no pattern of symptom frequency over time.
has issue date	2020-06-30(xsd:dateTime)
bibo:doi	10.1093/ofid/ofaa271
has license	cc-by-nc-nd
sha1sum (hex)	fa5187d5537874ebae32555c7667626da7d26de8
schema:url	https://doi.org/10.1093/ofid/ofaa271
resource representing a document's title	Symptoms of COVID-19 Outpatients in the United States
has PubMed Central identifier	PMC7337847
schema:publication	Open Forum Infect Dis
resource representing a document's body	covid:fa5187d5537874ebae32555c7667626da7d26de8#body_text
is schema:about of	covid:arg/fa5187d5537874ebae32555c7667626da7d26de8 named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'muscle aches' named entity 'COVID-19 Response Team' named entity 'infection' named entity 'infection' named entity 'Cough' named entity 'symptom' named entity 'infection' named entity 'SARS-CoV-2' named entity 'short duration' named entity 'signs and symptoms' named entity 'fever' named entity 'fatigue' named entity 'healthcare personnel' named entity 'significant difference' named entity 'infection' named entity 'pathogen' named entity 'asymptomatic' named entity 'fatigue' named entity 'shortness of breath' named entity 'intensive care unit' named entity 'infection' named entity 'infection' named entity 'infection' named entity '2, 3' named entity 'diarrhea' named entity 'fever' named entity 'infection' named entity 'sinus congestion' named entity 'rhinorrhea' named entity 'symptom' named entity 'infection' named entity 'COVID-19' named entity 'infection' named entity 'symptom' named entity 'healthcare workers' named entity 'diarrhea' named entity 'Italian' named entity 'infection' named entity 'mainland China' named entity 'SARS-CoV-1' named entity 'symptom' named entity 'long duration' named entity 'symptom' named entity 'ICU' named entity 'headache' named entity 'SARS-CoV-2' named entity 'rhinorrhea' named entity 'China' named entity 'infection' named entity 'symptom' named entity 'coronavirus' named entity 'Severe acute respiratory syndrome coronavirus 2' named entity 'cough' named entity 'infection' named entity 'high-risk' named entity 'myalgia' named entity 'CDC' named entity 'diarrhea' named entity 'smell or taste' named entity 'infection' named entity 'infection' named entity 'April 20, 2020' named entity 'SARS-CoV-2' named entity 'acute respiratory distress syndrome' named entity 'fatigue' named entity 'high-risk' named entity 'symptom profiles' named entity 'cough'

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