About: Cell-Type-Specific Expression of Renin-Angiotensin-System Components in the Human Body and Its Relevance to SARS-CoV-2 Infection

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Cell-Type-Specific Expression of Renin-Angiotensin-System Components in the Human Body and Its Relevance to SARS-CoV-2 Infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Cell-Type-Specific Expression of Renin-Angiotensin-System Components in the Human Body and Its Relevance to SARS-CoV-2 Infection
Creator	Tenoever, Benjamin Muthukumar, Thangamani Williams, Zev Morozov, Pavel Suryawanshi, Hemant Tuschl, Thomas Yamaji, Masashi
Source	BioRxiv
abstract	We have analyzed the cell-type-specific expression of the renin-angiotensin system (RAS) components across 141 cell types or subtypes as defined by single-cell RNA-seq (scRNA-seq) analysis. ACE2, one of the components of RAS, also facilitates SARS-CoV-2 entry into cells in cooperation with its associated protease TMPRSS2. Therefore, our analysis also contributes to the understanding of SARS-CoV-2 infection, spreading of the virus throughout the body, and potential viral interference with RAS in COVID-19 patients.
has issue date	2020-04-11(xsd:dateTime)
bibo:doi	10.1101/2020.04.11.034603
has license	biorxiv
sha1sum (hex)	fa79008d6463804afc5abb6cb16ba7c6bc3dc32d
schema:url	https://doi.org/10.1101/2020.04.11.034603
resource representing a document's title	Cell-Type-Specific Expression of Renin-Angiotensin-System Components in the Human Body and Its Relevance to SARS-CoV-2 Infection
schema:publication	bioRxiv
resource representing a document's body	covid:fa79008d6463804afc5abb6cb16ba7c6bc3dc32d#body_text
is schema:about of	named entity 'virus' named entity 'cells' named entity 'Components' named entity 'THE CELL' named entity 'COMPONENTS' named entity 'CELL TYPES' named entity 'SINGLE-CELL RNA-SEQ' named entity 'VIRAL INTERFERENCE' named entity 'SPREADING' named entity 'RAS' named entity 'TYPE' named entity 'patients' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'RAS' named entity 'RAS' named entity 'cooperation' named entity 'RAS' named entity 'RAS' named entity 'cell-type' named entity 'SARS-CoV-2' named entity 'TMPRSS2' named entity 'SARS-CoV-2' named entity 'Infection' named entity 'RAS' named entity 'TMPRSS2' named entity 'proximal tubular' named entity 'esophagus' named entity 'scRNA-seq' named entity 'TMPRSS2' named entity 'RNA-seq' named entity 'PI3K/Akt' named entity 'vascular endothelial cells' named entity 'cell types' named entity 'arachidonic acid' named entity 'allograft' named entity 'PLA2G4A' named entity 'epithelial' named entity 'cell types' named entity 'gastrointestinal tract' named entity 'signaling cascade' named entity 'ileum' named entity 'COVID-19' named entity 'scRNA-seq' named entity 'ciliated' named entity 'decidua' named entity 'virus' named entity 'gene expression' named entity 'cell-type' named entity 'kidney' named entity 'gastrointestinal tract' named entity 'biofluids' named entity 'RAS' named entity 'epithelial cell' named entity 'scRNA-seq' named entity 'MAP kinases' named entity 'esophagus' named entity 'AGTR1' named entity 'BALF' named entity 'esophagus' named entity 'rectum' named entity 'vascular endothelial cells' named entity 'tuberculosis' named entity 'expression profiles' named entity 'vascular endothelial cells' named entity 'RAS' named entity 'calcium' named entity 'extracellular RNA' named entity 'COVID-19 disease' named entity 'ACE2' named entity 'lung' named entity 'lung' named entity 'first-trimester' named entity 'placenta' named entity 'ACE2' named entity 'cell type' named entity 'virus' named entity 'expression profiles'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software