About: Varied clinical presentation and outcome of SARS‐CoV‐2 infection in liver transplant recipients: initial experience at a single center in Madrid, Spain

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About: Varied clinical presentation and outcome of SARS‐CoV‐2 infection in liver transplant recipients: initial experience at a single center in Madrid, Spain Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Varied clinical presentation and outcome of SARS‐CoV‐2 infection in liver transplant recipients: initial experience at a single center in Madrid, Spain
Creator	Fernández-Ruiz, Mario Aguado, José Lumbreras, Carlos Loinaz, Carmelo San Juan, Rafael Folgueira, María Asunción, María Asín, Pérez-Jacoiste Calvo, Jorge Cambra, Félix Caso, Oscar García-Sesma, Alvaro Justo, Iago Manrique, Alejandro Marcacuzco, Alberto
source	Medline; PMC
abstract	BACKGROUND: Which are the consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV2) infection in liver transplant (LT) recipients? METHODS: We attempted to address this question by reviewing our single‐center experience during the first two months of the pandemics at a high incidence area. RESULTS: Nineteen adult patients (5 females) were diagnosed by May 5th, 2020. Median age was 58 (range 55‐72), and median follow‐up since transplantation was 83 (range 20‐183) months. Cough (84.2%), fever (57.9%) and dyspnea (47.4%) were the most common symptoms. Thirteen patients (68.4%) had pneumonia in X‐ray/CT scan. Hydroxychloroquine was administered in 11 patients, associated with lopinavir/ritonavir and interferon β in 2 cases each. Immunomodulatory therapy with tocilizumab was used in 2 patients. Immunosuppression (IS) was halted in one patient, and modified in only other two due to potential drug interactions. Five (26.3%) patients were managed as outpatient. Two patients (10.5%) died, 10 (52.6%) were discharged home, and 2 (10.5%) were still hospitalized after a median follow‐up of 41 days from the onset of symptoms. Baseline IS regimen remained unchanged in all surviving recipients, with good liver function. CONCLUSIONS: Our preliminary experience shows a broad spectrum of disease severity in LT patients with COVID‐19, with a favorable outcome in most of them without needing to modify baseline IS.
has issue date	2020-06-20(xsd:dateTime)
bibo:doi	10.1111/tid.13372
bibo:pmid	32562561
has license	no-cc
sha1sum (hex)	fa8ddde9e33895fa5d2cf5bd37455de58f7d3633
schema:url	https://doi.org/10.1111/tid.13372
resource representing a document's title	Varied clinical presentation and outcome of SARS‐CoV‐2 infection in liver transplant recipients: initial experience at a single center in Madrid, Spain
has PubMed Central identifier	PMC7323090
has PubMed identifier	32562561
schema:publication	Transpl Infect Dis
resource representing a document's body	covid:fa8ddde9e33895fa5d2cf5bd37455de58f7d3633#body_text
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