About: A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs
Creator	Baumeister, Elsa María, Elena Avaro, Martín Benedetti, Estefanía Dattero, Florencia Rocca, María Ledesma, Martín Nachtigall, Fabiane Prieto, Mónica Russo, Mara Santos, Leonardo Vay, Carlos Zintgraff, Jonathan
source	BioRxiv
abstract	Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The rapid, sensitive and specific diagnosis of SARS-CoV-2 by fast and unambiguous testing is widely recognized to be critical in responding to the ongoing outbreak. Since the current testing capacity of RT-PCR-based methods is being challenged due to the extraordinary demand of supplies, such as RNA extraction kits and PCR reagents worldwide, alternative and/or complementary testing assays should be developed. Here, we exploit the potential of mass spectrometry technology combined with machine learning algorithms as an alternative fast tool for SARS-CoV-2 detection from nasopharyngeal swabs samples. According to our preliminary results, mass spectrometry-based methods combined with multivariate analysis showed an interesting potential as a complementary diagnostic tool and further steps should be focused on sample preparation protocols and the improvement of the technology applied.
has issue date	2020-05-07(xsd:dateTime)
bibo:doi	10.1101/2020.05.07.082925
has license	biorxiv
sha1sum (hex)	fae979a6ca888d452573a8b759d6e6cc62da808a
schema:url	https://doi.org/10.1101/2020.05.07.082925
resource representing a document's title	A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs
schema:publication	bioRxiv
resource representing a document's body	covid:fae979a6ca888d452573a8b759d6e6cc62da808a#body_text
is schema:about of	named entity 'RNA extraction' named entity 'exploit' named entity 'MALDI-TOF' named entity 'multivariate analysis' named entity 'BASED' named entity 'PROTOCOLS' named entity 'SUPPLIES' named entity 'swabs' named entity 'severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)' named entity 'diagnosis' named entity 'assays' named entity 'recognized' named entity 'alternative' named entity 'focused' named entity 'testing' named entity 'Combined' named entity 'tool' named entity 'RNA extraction' named entity 'MALDI-TOF' named entity 'algorithms' named entity 'clinical samples' named entity 'COVID' named entity 'MALDI' named entity 'COVID' named entity 'Ghent' named entity 'sensitivity, specificity' named entity 'analysis of the spectra' named entity 'RNA extraction' named entity 'biomarker' named entity 'Germany' named entity 'Bremen' named entity 'Bruker Daltonics' named entity 'SARS-CoV-2' named entity 'list calculation' named entity 'pathogenic viruses' named entity 'Biomarker' named entity 'lockdown measures' named entity 'vaccine' named entity 'SARS-CoV-2' named entity 'database' named entity 'database' named entity 'World Health Organization' named entity 'Bruker Daltonics' named entity 'coronavirus disease 2019' named entity 'Belgium' named entity 'Preprint' named entity 'assaying' named entity 'diagnostic tool' named entity 'MALDI-TOF MS' named entity 'statistical analysis' named entity 'scientific community' named entity 'COVID' named entity 'PCR' named entity 'RT-PCR' named entity 'Applied Maths' named entity 'COVID' named entity 'database' named entity 'SARS-CoV-2 virus' named entity 'Maldi' named entity 'healthcare systems' named entity 'SARS-CoV-2' named entity 'mzXML' named entity 'MALDI-TOF MS' named entity 'Wuhan' named entity 'MSPs' named entity 'MALDI-TOF MS' named entity 'Germany' named entity 'machine learning' named entity 'Germany' named entity 'SARS-CoV-2' named entity 'MSPs' named entity 'biomarkers'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software