About: IgY antibodies for the immunoprophylaxis and therapy of respiratory infections

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About: IgY antibodies for the immunoprophylaxis and therapy of respiratory infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	IgY antibodies for the immunoprophylaxis and therapy of respiratory infections
Creator	Abbas, Aymn Aly El-Kafrawy, Sherif Azhar, Ahmed Ibraheem, Esam Sartaj Sohrab, Sayed
source	Medline; PMC
abstract	Emergence of drug resistance among the causative organisms for respiratory tract infections represents a critical challenge to the global health care community. Further, although vaccination can prevent disease, vaccine development is impeded by several factors. Therefore, novel approaches to treat and manage respiratory infections are urgently needed. Passive immunization represents a possible alternative to meet this need. Immunoglobulin Y antibodies (IgYs) from the yolk of chicken eggs have previously been used against bacterial and viral infections in human and animals. Their advantages include lack of reaction with mammalian Fc receptors, low production cost, and ease of extraction. Compared to mammalian IgGs, they have higher target specificity and greater binding avidity. They also possess remarkable pathogen-neutralizing activity in the respiratory tract and lungs. In this review, we provide an overview of avian IgYs and describe their potential therapeutic applications for the prevention and treatment of respiratory infections.
has issue date	2018-09-19(xsd:dateTime)
bibo:doi	10.1080/21645515.2018.1514224
bibo:pmid	30230944
has license	cc-by-nc-nd
sha1sum (hex)	fc1f4b62e7c63ec2a3536401ce6aea880dca8512
schema:url	https://doi.org/10.1080/21645515.2018.1514224
resource representing a document's title	IgY antibodies for the immunoprophylaxis and therapy of respiratory infections
has PubMed Central identifier	PMC6363154
has PubMed identifier	30230944
schema:publication	Hum Vaccin Immunother
resource representing a document's body	covid:fc1f4b62e7c63ec2a3536401ce6aea880dca8512#body_text
is schema:about of	named entity 'NEED' named entity 'HEALTH CARE' named entity 'IMPEDED' named entity 'ANIMALS' named entity 'HUMAN' named entity 'THERAPEUTIC' named entity 'HAVE' named entity 'POTENTIAL' named entity 'GLOBAL HEALTH' named entity 'MEET' named entity 'REACTION' named entity 'POSSIBLE' named entity 'RESPIRATORY TRACT' named entity 'AVIAN' named entity 'BACTERIAL' named entity 'BINDING' named entity 'FC RECEPTORS' named entity 'antibodies' named entity 'IMMUNOPROPHYLAXIS' named entity 'APPROACHES' covid:arg/fc1f4b62e7c63ec2a3536401ce6aea880dca8512 named entity 'THEIR' named entity 'HIGHER' named entity 'COMMUNITY' named entity 'GREATER' named entity 'PREVENTION' named entity 'POSSESS' named entity 'MANAGE' named entity 'ALTERNATIVE' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'IGY' named entity 'ANTIBODIES' named entity 'LOW' named entity 'REVIEW' named entity 'LACK' named entity 'TARGET' named entity 'EXTRACTION' named entity 'NOVEL' named entity 'COMPARED' named entity 'EMERGENCE' named entity 'OVERVIEW' named entity 'APPLICATIONS' named entity 'USED' named entity 'PATHOGEN' named entity 'LUNGS' named entity 'ANTIBODIES' named entity 'THERAPY' named entity 'IMMUNOGLOBULIN Y' named entity 'COST' named entity 'ORGANISMS' named entity 'TREAT' named entity 'CHICKEN' named entity 'EGGS' named entity 'ACTIVITY' named entity 'RESPIRATORY INFECTIONS' named entity 'EASE' named entity 'PASSIVE IMMUNIZATION' named entity 'RESPIRATORY INFECTIONS' named entity 'DRUG RESISTANCE' named entity 'NEEDED' named entity 'AVIDITY' named entity 'TREATMENT' named entity 'DISEASE' named entity 'DESCRIBE' named entity 'PRODUCTION' named entity 'VACCINATION' named entity 'SPECIFICITY' named entity 'VIRAL INFECTIONS' named entity 'PROVIDE' named entity 'MAMMALIAN' named entity 'CRITICAL' named entity 'INCLUDE' named entity 'PREVENT' named entity 'CHALLENGE' named entity 'PREVIOUSLY' named entity 'VACCINE DEVELOPMENT' named entity 'YOLK'

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