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About:
Acute Pulmonary Embolism in Critically Ill Patients with COVID-19
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wasabi.inria.fr
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Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Acute Pulmonary Embolism in Critically Ill Patients with COVID-19
Creator
Alsmaan, Hafez
Biostatistician, &
Callahan, Cynthia
Clinical, Rheumatology
Fraenkel, Liana
Johansen, Mange
Manjunath, Madhura
Miranda, Julio
Oelberg, David
Paul, Research
Phinney, Blessing
Valli-Harwood, Georgianne
source
MedRxiv
abstract
Since the discovery of the novel coronavirus (SARS-Co-V-2) in December 2019, multiple characteristics have been reported, as our understanding of this new disease unfolds. One such association is its tendency to cause thromboembolic events, particularly venous thromboembolism (1,2). In a four-week period during the initial spread of COVID-19 at a 300 bed community hospital in western Massachusetts, 23 patients who were PCR positive for SARS-CoV-2 RNA required treatment in either the intensive care unit (ICU) or intermediate/step-down unit (SDU). All patients were treated with standard DVT prophylaxis from the time of admission, except for two patients who were on full anticoagulation for chronic atrial fibrillation. Of the 23 patients, 7 (30%) were diagnosed with acute, clinically significant, pulmonary embolism (PE). Four of the 7 manifested evidence of acute cor pulmonale, one of whom succumbed as a direct consequence of a massive PE. Other markers were reviewed in the 7 patients to identify trends that could allow for early suspicion of PE in COVID-19 patients. Although D-dimer tended to rise during the hospitalization relative to the control group, the results were inconsistent, and there were no other meaningful distinguishing features between the groups at the time of admission.
has issue date
2020-05-24
(
xsd:dateTime
)
bibo:doi
10.1101/2020.05.22.20110270
has license
medrxiv
sha1sum (hex)
fc409a102d03530d1da80a0027b260b0cfeb48ca
schema:url
https://doi.org/10.1101/2020.05.22.20110270
resource representing a document's title
Acute Pulmonary Embolism in Critically Ill Patients with COVID-19
resource representing a document's body
covid:fc409a102d03530d1da80a0027b260b0cfeb48ca#body_text
is
schema:about
of
named entity 'Acute'
named entity 'Pulmonary'
named entity 'COVID-19'
named entity 'Critically'
named entity 'Critical Care'
named entity 'Critically Ill Patients'
named entity 'hemorrhage'
named entity 'Heparin'
named entity 'high-risk'
named entity 'disseminated intravascular coagulation'
named entity 'D-dimer'
named entity 'medRxiv'
named entity 'anticoagulation'
named entity 'critically ill patients'
named entity 'Pittsfield'
named entity 'COVID-19'
named entity 'D-dimer'
named entity 'western Massachusetts'
named entity 'ICU'
named entity 'obstructive shock'
named entity 'pulmonary embolism'
named entity 'Informed consent'
named entity 'PESI'
named entity 'May 24'
named entity 'clinically significant'
named entity 'V-2'
named entity 'SARS-CoV-2'
named entity 'COVID'
named entity 'RNA'
named entity 'risk factors'
named entity 'control group'
named entity 'thrombolytic therapy'
named entity '5.7'
named entity 'D-dimer'
named entity 'autopsy'
named entity 'antiphospholipid antibodies'
named entity 'atrial fibrillation'
named entity 'CC-BY-NC-ND 4.0'
named entity 'subcutaneous'
named entity 'CT pulmonary angiography'
named entity 'transthoracic echocardiography'
named entity 'critically ill'
named entity 'ICU'
named entity 'COVID-19'
named entity 'DVT'
named entity 'anticoagulation'
named entity 'prophylaxis'
named entity 'gastrointestinal symptoms'
named entity 'D-dimer'
named entity 'control group'
named entity 'prophylaxis'
named entity 'D-dimer'
named entity 'DVT'
named entity 'tissue plasminogen activator'
named entity 'D-dimer'
named entity 'Enoxaparin'
named entity 'critically ill patients'
named entity 'coronavirus'
named entity 'pulmonary embolism severity index'
named entity 'medRxiv'
named entity 'ICU'
named entity 'subcutaneous'
named entity 'cor pulmonale'
named entity 'unfractionated heparin'
named entity 'D-dimer'
named entity 'clinical features'
named entity 'Wells score'
named entity 'medRxiv'
named entity 'linear regression'
named entity 'prophylactic'
named entity 'thromboembolic events'
named entity 'COVID'
named entity 'anticoagulation'
named entity 'resting heart rate'
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