About: Feeding associated neonatal necrotizing enterocolitis (Primary NEC) is an inflammatory bowel disease

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About: Feeding associated neonatal necrotizing enterocolitis (Primary NEC) is an inflammatory bowel disease Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Feeding associated neonatal necrotizing enterocolitis (Primary NEC) is an inflammatory bowel disease
Creator	Clark, David Munshi, Upender
Source	Elsevier; Medline; PMC
abstract	Abstract Neonatal necrotizing enterocolitis which develops after feeding preterm infants is characterized by severe intestinal inflammation and profound systemic metabolic acidosis. The fermentation of undigested dietary carbohydrate by colonic flora yields gases (CO2 and H2) and short chain organic acids. These organic acids can disrupt the intestinal mucosa and initiate inflammation driven predominantly by resident mast cells and by granulocytes which are recruited from blood. A systemic acidosis ensues derived from intestinal acids, not classic lactic acidosis produced from anaerobic metabolism. The systemic acidosis further compromises inflamed bowel leading to bowel necrosis.
has issue date	2014-02-28(xsd:dateTime)
bibo:doi	10.1016/j.pathophys.2013.11.006
bibo:pmid	24406172
has license	els-covid
sha1sum (hex)	fc4edae0cc815126a3fa1d29fe62cfb5d10a9b5a
schema:url	https://doi.org/10.1016/j.pathophys.2013.11.006
resource representing a document's title	Feeding associated neonatal necrotizing enterocolitis (Primary NEC) is an inflammatory bowel disease
has PubMed Central identifier	PMC7126559
has PubMed identifier	24406172
schema:publication	Pathophysiology
resource representing a document's body	covid:fc4edae0cc815126a3fa1d29fe62cfb5d10a9b5a#body_text
is schema:about of	named entity 'intestinal' named entity 'granulocytes' named entity 'lactic acidosis' named entity 'gases' named entity 'driven' named entity 'inflammation' named entity 'inflammatory bowel disease' named entity 'neonatal' named entity 'INTESTINAL' named entity 'GASES' named entity 'BLOOD' named entity 'FERMENTATION' named entity 'DIETARY CARBOHYDRATE' named entity 'RESIDENT' named entity 'BOWEL NECROSIS' named entity 'ACIDOSIS ' named entity 'INFLAMMATION' named entity 'FLORA' named entity 'ASSOCIATED' named entity 'NEC' named entity 'INFANTS' named entity 'DRIVEN' named entity 'INITIATE' named entity 'NEONATAL NECROTIZING ENTEROCOLITIS' named entity 'INFLAMMATORY BOWEL DISEASE' named entity 'FEEDING' named entity 'COMPROMISES' named entity 'CLASSIC' named entity 'GRANULOCYTES' named entity 'COLONIC' named entity 'METABOLIC ACIDOSIS' named entity 'CHAIN' named entity 'NEONATAL NECROTIZING ENTEROCOLITIS' named entity 'BOWEL' named entity 'DERIVED' named entity 'CHARACTERIZED' named entity 'THESE' named entity 'ANAEROBIC METABOLISM' named entity 'PRETERM' named entity 'ORGANIC ACIDS' named entity 'INTESTINAL MUCOSA' named entity 'ACIDS' named entity 'DEVELOPS' named entity 'MAST CELLS' named entity 'SHORT' named entity 'LACTIC ACIDOSIS' named entity 'SYSTEMIC' named entity 'LEADING' named entity 'INTESTINAL INFLAMMATION' named entity 'SEVERE' named entity 'AFTER FEEDING' named entity 'INFLAMED' named entity 'DISRUPT' named entity 'H 2' named entity 'PROFOUND' named entity 'yields' named entity 'flora' named entity 'classic' named entity 'infants' named entity 'short' named entity 'produced' named entity 'undigested' named entity 'inflammation' named entity 'inflammation' named entity 'carbohydrate' named entity 'systemic acidosis' named entity 'lactic acidosis' named entity 'organic acids' named entity 'Neonatal necrotizing enterocolitis' named entity 'anaerobic metabolism' named entity 'preterm' named entity 'perinatal' named entity 'organic acid' named entity 'preterm infants' named entity 'Staphylococcus' named entity 'hydrogen' named entity 'Klebsiella' named entity 'preterm infants' named entity 'ischemic' named entity 'NEC'

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