About: Bioprocess Engineering Issues That Would Be Faced in Producing a DNA Vaccine at up to 100 m(3) Fermentation Scale for an Influenza Pandemic

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About: Bioprocess Engineering Issues That Would Be Faced in Producing a DNA Vaccine at up to 100 m(3) Fermentation Scale for an Influenza Pandemic Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Bioprocess Engineering Issues That Would Be Faced in Producing a DNA Vaccine at up to 100 m(3) Fermentation Scale for an Influenza Pandemic
Creator	Ward, John Bracewell, Daniel Doig, Steven Dunnill, Peter Hoare, Mike Kong, Simyee Levy, M Titchener-Hooker, Nigel
Source	PMC
abstract	The risk of a pandemic with a virulent form of influenza is acknowledged by the World Health Organization (WHO) and other agencies. Current vaccine production facilities would be unable to meet the global requirement for vaccine. As a possible supplement a DNA vaccine may be appropriate, and bioprocess engineering factors bearing on the use of existing biopharmaceutical and antibiotics plants to produce it are described. This approach addresses the uncertainty of timing of a pandemic that precludes purpose‐built facilities. The strengths and weaknesses of alternative downstream processing routes are analyzed, and several gaps in public domain information are addressed. The conclusion is that such processing would be challenging but feasible.
has issue date	2008-09-05(xsd:dateTime)
bibo:doi	10.1021/bp050190n
bibo:pmid	16321039
has license	no-cc
sha1sum (hex)	fca4a578e65771f9b87e3ccb2004fb198d089285
schema:url	https://doi.org/10.1021/bp050190n
resource representing a document's title	Bioprocess Engineering Issues That Would Be Faced in Producing a DNA Vaccine at up to 100 m(3) Fermentation Scale for an Influenza Pandemic
has PubMed Central identifier	PMC7161863
has PubMed identifier	16321039
schema:publication	Biotechnol Prog
resource representing a document's body	covid:fca4a578e65771f9b87e3ccb2004fb198d089285#body_text
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