About: Transmission of corona virus disease 2019 during the incubation period may lead to a quarantine loophole

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Transmission of corona virus disease 2019 during the incubation period may lead to a quarantine loophole
Creator	Zhao, Xin Xia, Wei Liu, Juan Zhang, Yu Li, Yuanyuan Li, Ying Yu, Ling Wang, Meng Liu, Qi Xu, Qing Wang, Qianqian Cao, Shuting Ding, Xingjuan Fang, ; Feng Qiu, ; Huan, Shu Li, Chunhui Liao, Jiaqiang Lin, ; Ma, Jiaolong Mahai, Gaga Namat, Asmagvl Qian, Xi Qu, Jingyu Ruan, Fengyu Shi, Lisha Sun, ; Wang, Aizhen Wang, Hanjin Xiao, Jiying Xing, Yuling Xu, Hongbo Xu, Shunqing
source	MedRxiv
abstract	Background: The ongoing outbreak of novel corona virus disease 2019 (COVID-19) in Wuhan, China, is arousing international concern. This study evaluated whether and when the infected but asymptomatic cases during the incubation period could infect others. Methods: We collected data on demographic characteristics, exposure history, and symptom onset day of the confirmed cases, which had been announced by the Chinese local authorities. We evaluated the potential of transmission during the incubation period in 50 infection clusters, including 124 cases. All the secondary cases had a history of contact with their first-generation cases prior to symptom onset. Results: The estimated mean incubation period for COVID-19 was 4.9 days (95% confidence interval [CI], 4.4 to 5.4) days, ranging from 0.8 to 11.1 days (2.5th to 97.5th percentile). The observed mean and standard deviation (SD) of serial interval was 4.1±3.3 days, with the 2.5th and 97.5th percentiles at -1 and 13 days. The infectious curve showed that in 73.0% of the secondary cases, their date of getting infected was before symptom onset of the first-generation cases, particularly in the last three days of the incubation period. Conclusions: The results indicated the transmission of COVID-9 occurs among close contacts during the incubation period, which may lead to a quarantine loophole. Strong and effective countermeasures should be implemented to prevent or mitigate asymptomatic transmission during the incubation period in populations at high risk.
has issue date	2020-03-08(xsd:dateTime)
bibo:doi	10.1101/2020.03.06.20031955
has license	medrxiv
sha1sum (hex)	fd96fc1859201e13e35526c188e022fa6e335327
schema:url	https://doi.org/10.1101/2020.03.06.20031955
resource representing a document's title	Transmission of corona virus disease 2019 during the incubation period may lead to a quarantine loophole
resource representing a document's body	covid:fd96fc1859201e13e35526c188e022fa6e335327#body_text
is schema:about of	named entity 'INCUBATION PERIOD' named entity 'corona virus' named entity 'asymptomatic' named entity 'incubation period' named entity 'disease' named entity 'lead' named entity 'NOVEL' named entity 'STUDY' named entity 'INTERNATIONAL' named entity 'ONGOING' named entity 'OUTBREAK' named entity 'ASYMPTOMATIC' named entity 'CASES' named entity 'INFECT' named entity 'VIRUS DISEASE' named entity 'BUT' named entity 'QUARANTINE' named entity '2019' named entity 'TRANSMISSION' named entity 'CORONA' named entity 'INCUBATION PERIOD' named entity 'CORONA' named entity 'CONCERN' named entity 'AROUSING' named entity 'INFECTED' named entity 'VIRUS DISEASE' named entity 'WUHAN' named entity 'EVALUATED' named entity 'CHINA' named entity '2019' named entity 'LEAD' covid:arg/fd96fc1859201e13e35526c188e022fa6e335327 named entity 'study' named entity '2019' named entity 'incubation period' named entity 'asymptomatic' named entity 'Wuhan' named entity 'Wuhan' named entity 'serial interval' named entity 'sample size' named entity 'serial interval' named entity 'China' named entity 'CC-BY-ND' named entity 'serial interval' named entity 'incubation period' named entity '95% confidence interval' named entity 'asymptomatic' named entity 'preprint' named entity '5.2' named entity 'preprint' named entity 'infection' named entity 'doi' named entity 'COVID'

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