About: Tissue Culture in the Laboratory Diagnosis of Viral Infections

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Tissue Culture in the Laboratory Diagnosis of Viral Infections
Creator	Schmidt, Nathalie
Source	PMC
abstract	The use of both rhesus monkey kidney and human fetal diploid cell cultures for attempts to isolate virus from human clinical specimens recovered approximately 30% more isolates from fecal, throat, skin lesion, and tissue specimens than were recovered in a single cell culture system. The sensitivities of the two cell types for isolation of viruses in the major groups infecting man are compared. The use of both BS-C-1 and RK-13 cells yielded approximately 25% more rubella virus isolates than were recovered in a single cell system. Procedures such as the establishment of cell cultures from tissues suspected of harboring viruses, cocultivation of cells from biopsy or autopsy specimens with other cell types, and the use of organ cultures, have in certain situations resulted in greater sensitivity for recovery of viruses. Micro cell culture tests have been devised for virus identification and antibody assays; these are far more economical than conventional tests in terms of reagents, space requirements, and personnel time. Methods have been developed for the production of higher-titered viral serologic antigens in cell culture systems.
has issue date	1972-06-01(xsd:dateTime)
bibo:doi	10.1093/ajcp/57.6.820
bibo:pmid	4337372
has license	no-cc
sha1sum (hex)	fe52a063c23c7544c2c30bdd871271975595fe08
schema:url	https://doi.org/10.1093/ajcp/57.6.820
resource representing a document's title	Tissue Culture in the Laboratory Diagnosis of Viral Infections
has PubMed Central identifier	PMC7109857
has PubMed identifier	4337372
schema:publication	Am J Clin Pathol
resource representing a document's body	covid:fe52a063c23c7544c2c30bdd871271975595fe08#body_text
is schema:about of	named entity 'diagnosis' named entity 'greater' named entity 'rubella virus' named entity 'cell culture' named entity 'cell' named entity 'isolation' named entity 'isolate' named entity 'SENSITIVITY' named entity 'COMPARED' covid:arg/fe52a063c23c7544c2c30bdd871271975595fe08 named entity 'cell culture' named entity 'fetal' named entity 'viruses' named entity 'specimens' named entity 'recovered' named entity 'cell types' named entity 'skin lesion' named entity 'Culture' named entity 'single cell' named entity 'cell culture' named entity 'antibody' named entity 'viruses' named entity 'kidney' named entity 'Procedures' named entity 'human' named entity 'mice' named entity 'diploid cell' named entity 'organ' named entity 'vaccinia virus' named entity 'serologic' named entity 'virus' named entity 'antigens' named entity 'undifferentiated cells' named entity 'subacute sclerosing panencephalitis' named entity 'cell cultures' named entity 'virus' named entity 'viral antigens' named entity 'kidney cells' named entity 'cellular growth' named entity 'viruses' named entity 'viruses' named entity 'metabolic' named entity 'viruses' named entity 'sonication' named entity 'herpes simplex' named entity 'neutralization tests' named entity 'virus' named entity 'microneutralization' named entity 'clinical specimen' named entity 'common colds' named entity 'Fluorescent antibody' named entity 'cell culture' named entity 'TISSUE CULTURE' named entity 'SSPE' named entity 'antibody' named entity 'Diploid' named entity 'incubation' named entity 'clinical specimen' named entity 'viruses' named entity 'cell culture' named entity 'cell cultures' named entity 'biopsy' named entity 'enterovirus' named entity 'Rubella virus' named entity 'cell culture' named entity 'virus' named entity 'viruses' named entity 'diagnostic purposes' named entity 'virus' named entity 'diploid' named entity 'inoculum' named entity 'Microneutralization' named entity 'trypsinized' named entity 'measles virus' named entity 'organ' named entity 'viruses' named entity 'cell culture' named entity 'antigens' named entity 'cell lines' named entity 'autopsy' named entity 'cytomegalovirus'

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