About: Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: meta-analysis of the epidemiological evidence

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About: Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: meta-analysis of the epidemiological evidence Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: meta-analysis of the epidemiological evidence
Creator	Carolina, Ana Bonato, Soares Carolina, Rafaela De Carvalho Sales-Peres, Matheus Ferreira, Joel Helena, Silvia José De Azevedo-Silva, Lucas Junior, Santiago Pinto, Silvia Sales-Peres, Carvalho
Source	Elsevier; Medline; PMC
abstract	OBJECTIVES: To investigate the relationship between coronavirus disease 2019 (COVID-19) and obesity in critically ill patients admitted to the intensive care unit (ICU). METHODS: We systematically searched PubMed, SCOPUS, Embase, LILACS, and Web of Science for studies published up to April 27, 2020. The outcome of interest was composite poor outcome, comprising mortality and severe COVID-19. We used a standardized data extraction form to collect information from published reports of eligible studies. Heterogeneity and publication bias were assessed using I(2) statistic and funnel plots, respectively. RESULTS: Nine studies including 6,577 patients were selected for evaluation. The COVID-19 patients were 59.80% male and had comorbidities such as hypertension (51.51%), diabetes (30.3%), cardiovascular disease (16.66%), lung disease (15.99%), renal disease (7.49%), cancer (5.07%), and immunosuppression (1.8%). For patients with severe complications, the overall pooled event rates were 56.2% (random; 95% CI: 35.3-75.1; p = 0.015; I(2) = 71.461) for obesity, 23.6% (random; 95% CI: 17.9-30.5; p = 0.000; I(2) = 87.705) for type 2 diabetes, 45.9% (random; 95% CI: 38.0-53.9; p = 0.000; I(2) = 90.152) for hypertension, 20.0% (random; 95% CI: 7.9-42.0; p = 0.000; I(2) = 94.577) for smoking, 21.6% (random; 95% CI: 14.1-31.4%; p = 0.000, I(2) = 92.983) for lung diseases, and 20.6% (random; 95% CI: 15.2-27.5; p = 0.000, I(2) = 85.735) for cardiovascular diseases. DISCUSSION: This systematic review indicated the relationship between obesity, ICU admission, severe COVID-19, and disease progression in patients with COVID-19. Obese patients with hypertension, type 2 diabetes, smoking habit, lung disease, and/or cardiovascular disease should be cared for with increased attention.
has issue date	2020-08-03(xsd:dateTime)
bibo:doi	10.1016/j.orcp.2020.07.007
bibo:pmid	32773297
has license	no-cc
sha1sum (hex)	ffaafc257e7b8b86f2b98f7ec3ae50cc6ceb4803
schema:url	https://doi.org/10.1016/j.orcp.2020.07.007
resource representing a document's title	Coronavirus (SARS-CoV-2) and the risk of obesity for critically illness and ICU admitted: meta-analysis of the epidemiological evidence
has PubMed Central identifier	PMC7396969
has PubMed identifier	32773297
schema:publication	Obes Res Clin Pract
resource representing a document's body	covid:ffaafc257e7b8b86f2b98f7ec3ae50cc6ceb4803#body_text
is schema:about of	named entity 'Journal' named entity 'illness' named entity 'Coronavirus' named entity 'SARS-CoV-2' named entity 'epidemiological' named entity '95% CI' named entity 'exhaled breath' named entity 'obesity' named entity 'systematic review' named entity 'metaanalysis' named entity 'mechanical ventilation' named entity 'systematic review' named entity 'pro-inflammatory cytokine' named entity 'SARS-CoV-2' named entity 'diaphragm' named entity 'influenza pandemic' named entity 'statistical unit' named entity 'COVID' named entity 'preexisting conditions' named entity 'diabetes' named entity 'leptin' named entity 'Systematic Reviews' named entity 'Coronavirus disease 2019' named entity 'meta-analysis' named entity 'obesity' named entity 'obesity' named entity 'infection prevention' named entity 'lung disease' named entity 'diabetes' named entity 'obesity' named entity 'oxygen' named entity 'hypertension' named entity 'meta-analysis' named entity 'obesity' named entity 'lung' named entity 'IL-6' named entity 'Spain' named entity 'COVID' named entity 'sample size' named entity '95% CI' named entity 'COVID' named entity 'obese' named entity 'metaanalysis' named entity 'SARS-CoV-2' named entity 'viral infection' named entity 'critically ill' named entity 'macrophage' named entity 'cardiovascular diseases' named entity 'opinion articles' named entity 'flowchart' named entity 'SARS-CoV-2' named entity 'obese' named entity 'ICU' named entity 'smokers' named entity 'ICU' named entity 'obesity' named entity 'obesity' named entity 'pulmonary disease' named entity 'critical illness' named entity 'virus' named entity 'ECMO' named entity 'diabetes' named entity 'immune responses' named entity 'meta-analysis' named entity 'comorbidities' named entity '95% CI' named entity 'hypertension' named entity 'obese' named entity 'covid-19' named entity 'lung disease' named entity 'COVID' named entity 'COVID'

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