About: author summary textual entity

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About: author summary textual entity Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Class
label	author summary textual entity
subClassOf	textual entity
described by	proxy:entity/http/purl.obolibrary.org/obo/iao.owl https://covidontheweb.inria.fr:4443/about/id/entity/http/purl.obolibrary.org/obo/iao.owl
term tracker item	https://github.com/information-artifact-ontology/IAO/issues/183
term editor	PERSON: Bill Baumgartner
example of usage	From Pendse et al. BMC Genomics. 2013; 14: 136. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608171/): The search for genetic risk factors for common human diseases often relies on the use of linkage and association studies to establish correlation between genomic markers and disease risk. These studies require additional functional evaluation of candidate genes, including their possible interaction with diet and environment. The number of candidate genes is typically large and the development of appropriate genetic tools in mammalian systems is slow. By contrast, large-scale genetic screens, using widely available genetic tools, are routinely conducted in the fruit fly Drosophila melanogaster. In this study, we used Drosophila to screen candidate genes identified in human genome-wide scans as associated with risk of metabolic abnormalities such as type 2 diabetes. We show that a number of human candidate genes have fly orthologs that play an important role in Drosophila tolerance to high dietary sucrose. We further explored some of the specific metabolic abnormalities that can result when these genes’ activities are reduced in flies, focusing on a gene we call dHHEX (CG7056), the fly ortholog of human HHEX.
definition	A textual entity, distinct from the abstract, that describes the significance and broader context of the document content. The author summary is often written in a non-technical manner and is aimed at both scientists and non-scientist readers, e.g as described in the article submission guidelines for PLoS Genetics (http://journals.plos.org/plosgenetics/s/submission-guidelines).
definition source	Article submission guidelines for PLoS Genetics (http://journals.plos.org/plosgenetics/s/submission-guidelines).
editor preferred term	author summary textual entity
is someValuesFrom of	nodeID://b662809867 nodeID://b662810236 nodeID://b663276499 nodeID://b663277879 nodeID://b665122130 nodeID://b665122499 nodeID://b665176589 nodeID://b665177057 nodeID://b665459146 nodeID://b665459516 nodeID://b665793700 nodeID://b665794069 nodeID://b665795398 nodeID://b665795767 nodeID://b665857198 nodeID://b665857567 nodeID://b665970961 nodeID://b665971330 nodeID://b666092935 nodeID://b666093304
is topic of	Information Artifact Ontology (IAO)

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