About: cross-linking immunoprecipitation high-throughput sequencing assay   Goto Sponge  NotDistinct  Permalink

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type
label
  • cross-linking immunoprecipitation high-throughput sequencing assay
subClassOf
described by
term editor
  • Jie Zheng
  • Chris Stoeckert
  • Venkat Malladi
example of usage
  • Heulga et al. Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins. Cell Rep. 2012 Feb 23;1(2):167-78. [PMID:22574288]
definition
  • An analyte assay that employs UV-crosslinking between RNA and a protein, followed by immunoprecipitation with antibodies for the protein, fragmentation, and high-throughput screening for RNA sequences that interact with a particular RNA-binding protein.
definition source
  • PMID:18978773
alternative label
  • CLIP-seq
  • HITS-CLIP
  • CLIP-seq assay
editor preferred term
  • cross-linking immunoprecipitation high-throughput sequencing assay
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