About: variance stabilizing transformation

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Attributes	Values
type	Class
label	variance stabilizing transformation
subClassOf	normalization data transformation nodeID://b665198974 nodeID://b665223271 nodeID://b665821793 nodeID://b665846090 nodeID://b665878305 nodeID://b665902602 nodeID://b665926899 nodeID://b665951196 nodeID://b669086829 nodeID://b669111014
described by	proxy:entity/http/purl.obolibrary.org/obo/obi.owl
term editor	James Malone Melanie Courtot Elisabetta Manduchi
example of usage	This can be used for expression microarray assay normalization and it is referred to as "variance stabilizing normalization", according to the procedure described e.g. in PMID 12169536.
definition	A variance stabilizing transformation is a data transformation, described in PMID 12169536, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (6) in this paper. One of the goals is to obtain an output matrix whose rows have equal variances. The method relies on various assumptions described in the paper.
definition source	PMID: 12169536
alternative label	variance stabilising transformation
editor preferred term	variance stabilizing transformation
has curation status	ready for release
is topic of	Ontology for Biomedical Investigations
is hasBody of	named entity 'VARIANCE STABILISING TRANSFORMATION'

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