Pio Laghi (21 May 1922 – 10 January 2009) was an Italian cardinal of the Catholic Church. His service was primarily in the diplomatic service of the Holy See and the Roman Curia. He served as Apostolic nuncio to several countries and as the Prefect of the Congregation for Catholic Education. He was elevated to the cardinalate in 1991. Cardinal Laghi was Pope John Paul II's secret emissary to the White House and to several presidents of the United States. He had a particularly close relationship with George H. W. Bush, and George W. Bush.