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Subject Item

dbr:Androstanolone

rdf:type

n15:ChemicalObject wd:Q8386 owl:Thing dbo:ChemicalSubstance dbo:Drug

rdfs:label

Androstanolone

rdfs:comment

Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men. It is also used to treat breast development and small penis in males. It is typically given as a gel for application to the skin, but can also be used as an ester by injection into muscle.

rdfs:seeAlso

dbr:Anabolic_steroid dbr:List_of_androgens dbr:List_of_androgen_esters dbr:Anabolic_steroids

owl:sameAs

wd:Q31686490 dbr:Androstanolone dbpedia-vi:Androstanolone n36:2vmou n38:02t62k

foaf:topic

dbr:ATCvet_code_QG03BB02 n7:_An–Ap dbr:List_of_androgens_and_anabolic_steroids dbr:Protona dbr:List_of_sex-hormonal_aqueous_suspensions dbr:Androgel-DHT dbr:Megestrol_acetate wikipedia-en:Androstanolone dbr:Ethisterone dbr:Stanaprol dbr:Stanolone dbr:C19H30O2 dbr:Proteina dbr:Trimethyltrienolone dbr:Stanozolol dbr:Sex-hormonal_agent dbr:ATC_code_A14AA01 dbr:Ophtovital dbr:ATC_code_A14 dbr:Dihydrotestosterone_undecanoate dbr:ATCvet_code_QA14AA01 dbr:ATC_code_G03 dbr:Dihydrotestosterone dbr:Androgen_ester dbr:Cristerona_MB dbr:Cristerona dbr:Mestanolone dbr:Sex_hormone-binding_globulin dbr:Prasterone n25: dbr:Anaboleen n27: dbr:Levonorgestrel dbr:Anabolex dbr:17α-Ethynyl-3β-androstanediol dbr:Nomegestrol_acetate dbr:ATC_code_G03BB02 dbr:Neodrol dbr:Androstanediol dbr:Etiocholanediol n33: dbr:Gelovit n34:this dbr:Androstenolone dbr:Androlone dbr:Androstanolone_valerate dbr:Androstanolone_enanthate dbr:Androstanolone_propionate dbr:Androstanolone_benzoate dbr:Andractim dbr:Polycystic_ovary_syndrome dbr:List_of_androgen_esters dbr:Anaprotin dbr:Neoprol dbr:AndroGel-DHT dbr:Controlled_Drugs_and_Substances_Act dbr:List_of_androstanes dbr:Stanadrol n39:anabolic_steroids_available_in_the_United_States dbr:Gynecomastia n40: dbr:Anabolic_steroid dbr:Danazol

foaf:depiction

n13:png n14:svg

wdrs:describedby

n9:Bicyclic_molecule n9:Polycythemia n19:Oral_administration n19:Redox n19:Adverse_effect n9:Cachexia n9:Androstane n9:Europe n19:Metabolism n9:Metabolism n9:Oral_administration n9:Bioassay n9:Belgium n9:Hematocrit n9:Gynecomastia

dbp:bioavailability

Transdermal: 10% Oral: Very low injection: 100%

dbp:drugbank

DB02901

dbp:eliminationHalfLife

10080.0

dbp:excretion

dbr:Urine

dbp:pregnancyCategory

X

dbp:tradename

Andractim, others

dct:subject

dbc:Secondary_alcohols dbc:Ketones dbc:Androstanes dbc:Androgens_and_anabolic_steroids dbc:World_Anti-Doping_Agency_prohibited_substances dbc:5α-Reduced_steroid_metabolites dbc:Estrogens dbc:Testosterone dbc:GABAA_receptor_positive_allosteric_modulators

dbo:wikiPageID

54432896

dbo:wikiPageRevisionID

1097459410

dbo:wikiPageWikiLink

dbr:Aromatase dbr:Chemical_derivative dbr:Pharmacokinetics dbr:EC50 dbr:Voice_deepening dbr:Gel dbr:Androstane dbc:Secondary_alcohols dbr:Furan dbr:World_Anti-Doping_Agency dbr:Acne dbr:France dbr:Cachexia dbr:Skin dbr:Injectable dbc:Ketones dbr:Mild_androgen_insensitivity_syndrome dbr:Cancer dbr:Facial_hair dbr:Bioavailability dbr:Human_serum_albumin dbr:Dihydrotestosterone_acetate dbr:Controlled_Substances_Act dbr:Dihydrotestosterone_butyrate dbr:Dihydrotestosterone_formate dbr:Oral_administration dbr:Australia dbr:Brain dbr:Sex_hormone-binding_globulin dbr:Menstrual_irregularity n16: dbr:Stenbolone dbr:Methasterone dbr:Edema dbr:Osteoporosis dbr:Mepitiostane dbr:Hydroalcoholic dbr:Methylepitiostanol dbr:Puberty dbr:Pattern_hair_loss dbr:Bicyclic_molecule dbr:Oil dbr:17α-alkylated_anabolic_steroid dbr:Aggressiveness dbr:Transdermal dbr:Polycythemia dbr:1-Testosterone dbr:Anabolic dbr:Muscle_hypertrophy dbc:Androstanes dbr:3α-androstanediol dbr:Double_bond dbr:Canada dbr:3α-hydroxysteroid_dehydrogenase n21: dbr:Epitiostanol dbr:Infertility dbr:Redox dbr:Topical_medication dbr:Oily_skin dbr:Dissociation_rate dbr:Oxandrolone dbc:Androgens_and_anabolic_steroids dbr:Androisoxazole dbr:Red_blood_cell dbc:World_Anti-Doping_Agency_prohibited_substances dbr:Mebolazine dbr:5α-reductase dbr:Skeletal_muscle dbr:Urine dbr:Europe dbr:Prostanozol dbr:Hypogonadism dbr:Spain dbr:Breast_atrophy dbr:Buccal_administration dbr:17α-Alkylated_anabolic_steroid n23: dbr:Adolf_Butenandt dbr:Azine dbr:Drug_form dbr:Embolism dbr:Luxembourg dbr:Methyl-1-testosterone dbr:Prostate_gland dbr:Micropenis dbr:Terminal_half-life dbr:Hepatotoxicity dbr:Androgen dbr:Mestanolone dbr:Testicular_atrophy dbr:Mesterolone dbr:Thrombosis dbr:Synthetic_compound dbr:Breast_cancer n24: dbr:Route_of_administration dbr:Oxymetholone dbr:Erythropoiesis dbr:Dihydrotestosterone_ester dbr:Testosterone dbr:Bolazine dbr:Biological_target dbr:Aqueous_suspension dbc:5α-Reduced_steroid_metabolites dbr:Italy dbr:Clitoromegaly dbr:Hydroxyl_group dbc:Estrogens n26: dbr:Drostanolone dbr:Drostanolone_propionate dbr:Postmenopause dbr:Cellulite dbr:Androgen_receptor dbr:Hematocrit dbr:United_States dbr:Intramuscular_injection dbr:Hair_growth dbr:United_Kingdom dbr:Sublingual_administration dbr:Stroke dbr:Corticosteroid-binding_globulin dbr:Oil_solution dbr:Side_effect dbr:Transgender_men dbr:Partial_androgen_insensitivity_syndrome dbr:Sex_hormone dbr:Transdermal_administration dbr:Phases_of_clinical_research dbr:Depot_injection dbr:Hirsutism dbr:Anabolic_steroid dbr:Androgen_replacement_therapy dbr:Seborrhea dbr:Ketone_group dbr:Hyperandrogenism dbr:Myotrophy dbr:Furazabol dbr:Desoxymethyltestosterone n32: dbr:Body_hair dbr:Androstanolone_ester dbr:Ether dbc:Testosterone dbr:Libido dbr:Metabolism dbr:Ester dbr:Plasma_protein_binding dbr:Hydrogenation dbr:Prostate_cancer dbr:Bone_mineral_density dbr:Sex_drive dbr:Adverse_effect dbr:Bioassay dbr:Benign_prostatic_hyperplasia dbr:Pharmacodynamics dbr:Androgen_ester dbr:Agonist dbr:Controlled_substance dbr:Virilization dbr:Germany dbr:Mesabolone dbr:Lysine dbr:Natural_product dbr:Symptom n37: dbr:Methylstenbolone dbr:Isoxazole dbr:Prodrug dbr:Microcrystalline dbr:Belgium dbr:Liver dbr:Hair_follicle dbr:Stanozolol dbr:Cardiovascular_system dbr:Metenolone dbr:Medicine dbr:Gynecomastia dbr:Cholesterol dbr:Pyrazole dbc:GABAA_receptor_positive_allosteric_modulators dbr:Androstanolone_valerate dbr:Steroid dbr:Androstanolone_benzoate dbr:Pharmaceutical_drug dbr:Androstanolone_enanthate dbr:Androstanolone_propionate dbr:Clinical_trial

dbo:wikiPageExternalLink

n31:800011409 n31:800016161 n31:800019178

foaf:isPrimaryTopicOf

wikipedia-en:Androstanolone

prov:wasDerivedFrom

n30:0

dbo:abstract

Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men. It is also used to treat breast development and small penis in males. It is typically given as a gel for application to the skin, but can also be used as an ester by injection into muscle. Side effects of androstanolone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. The medication is a naturally occurring androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and DHT. It has strong androgenic effects and weak muscle-building effects, as well as no estrogenic effects. Androstanolone was discovered in 1935 and was introduced for medical use in 1953. It is used mostly in France and Belgium. The drug has been used by weightlifters to increase performance due to its powerful androgenic properties. The medication is a controlled substance in many countries and so non-medical use is generally illicit.

dbo:thumbnail

n20:300

dbp:c

19

dbp:class

dbr:Androgen dbr:Anabolic_steroid

dbp:h

30

dbp:image

Dihydrotestosterone molecule ball.png

dbp:title

dbr:Pharmacodynamics

dbp:titlestyle

background:#ccccff

dbp:width

225

dbp:iupharLigand

2856

dbp:atcPrefix

A14

dbp:atcSuffix

AA01

dbp:metabolism

dbr:Liver

dbp:casNumber

521

dbp:chebi

16330

dbp:chembl

27769

dbp:chemspiderid

10189

dbp:iupacName

-17

dbp:o

2

dbp:pubchem

10635

dbp:routesOfAdministration

Transdermal , in the cheek, under the tongue, intramuscular injection

dbp:smiles

O=C4C[C@@H]3CC[C@@H]2[C@H][C@@]3CC4

dbp:stdinchi

1

dbp:stdinchikey

NVKAWKQGWWIWPM-ABEVXSGRSA-N

dbp:synonyms

Stanolone; Dihydrotestosterone; DHT; 5α-Dihydrotestosterone; 5α-DHT

dbp:unii

8

dbp:verifiedfields

verified

dbp:verifiedrevid

459443200

dbp:watchedfields

verified

dbo:alternativeName

Andractim, others

dbo:casNumber

521-18-6

dbo:chEBI

16330

dbo:chEMBL

27769

dbo:drugbank

DB02901

dbo:fdaUniiCode

08J2K08A3Y

dbo:pubchem

10635

dbo:class

dbr:Androgen dbr:Anabolic_steroid

dbo:wikiPageLength

42184

dbp:wikiPageUsesTemplate

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