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Subject Item
dbr:KaiC
rdf:type
dbo:Protein
rdfs:label
KaiC
rdfs:comment
KaiC is a gene belonging to the KaiABC gene cluster (with KaiA, and KaiB) that, together, regulate bacterial circadian rhythms, specifically in cyanobacteria. KaiC encodes for the KaiC protein, which interacts with the KaiA and KaiB proteins in a post-translational oscillator (PTO). The PTO is cyanobacteria master clock that is controlled by sequences of phosphorylation of KaiC protein. Regulation of KaiABC expression and KaiABC phosphorylation is essential for cyanobacteria circadian rhythmicity, and is particularly important for regulating cyanobacteria processes such as nitrogen fixation, photosynthesis, and cell division. Studies have shown similarities to Drosophila, Neurospora, and mammalian clock models in that the kaiABC regulation of the cyanobacteria slave circadian clock is also
owl:sameAs
dbr:KaiC wd:Q17155036 n18:gJbS n32:0t53vsy
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kaiC
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dbr:Biological_tests_of_necessity_and_sufficiency dbr:Circadian_rhythm dbr:Transcription_translation_feedback_loop dbr:Takao_Kondo dbr:Susan_Golden dbr:Society_for_Research_on_Biological_Rhythms dbr:Circadian_clock dbr:Takao_Kondo__Takao_Kondo__1 wikipedia-en:KaiC dbr:Cyanobacterial_clock_proteins n33:_Johnson n34:this n35:_Partch dbr:Dual_circadian_oscillator_model dbr:KAIC n36: dbr:KaiB n38: dbr:KaiA dbr:Circadian_advantage
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n7: n13:GTPase n17:Arginine n23:Gene_expression n17:Autocatalysis n17:Messenger_RNA n13:Photosynthesis n17:Genome n17:DnaB_helicase n17:Gene n13:Amino_acid n17:DNA n17:Aspartic_acid n17:Phase_shift n17:Amino_acid n17:Susan_Golden n40:
dct:subject
dbc:Gene_expression dbc:Circadian_rhythm
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39103747
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1085842505
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wikipedia-en:KaiC
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dbo:abstract
KaiC is a gene belonging to the KaiABC gene cluster (with KaiA, and KaiB) that, together, regulate bacterial circadian rhythms, specifically in cyanobacteria. KaiC encodes for the KaiC protein, which interacts with the KaiA and KaiB proteins in a post-translational oscillator (PTO). The PTO is cyanobacteria master clock that is controlled by sequences of phosphorylation of KaiC protein. Regulation of KaiABC expression and KaiABC phosphorylation is essential for cyanobacteria circadian rhythmicity, and is particularly important for regulating cyanobacteria processes such as nitrogen fixation, photosynthesis, and cell division. Studies have shown similarities to Drosophila, Neurospora, and mammalian clock models in that the kaiABC regulation of the cyanobacteria slave circadian clock is also based on a transcription translation feedback loop (TTFL). KaiC protein has both auto-kinase and auto-phosphatase activity and functions as the circadian regulator in both the PTO and the TTFL. KaiC has been found to not only suppress kaiBC when overexpressed, but also suppress circadian expression of all genes in the cyanobacterial genome.
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dbp:symbol
kaiC
dbp:entrezgene
3773504
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Q79PF4
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1240109
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1238550
dbp:organism
S. elongatus
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YP_400233.1
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