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Subject Item

n2:topic_0736

rdf:type

owl:Class

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Protein folds and structural domains

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This includes trans- or intra-membrane regions of a protein, typically describing physicochemical properties of the secondary structure elements. For example, the location and size of the membrane spanning segments and intervening loop regions, transmembrane region IN/OUT orientation relative to the membrane, plus the following data for each amino acid: A Z-coordinate (the distance to the membrane center), the free energy of membrane insertion (calculated in a sliding window over the sequence) and a reliability score. The z-coordinate implies information about re-entrant helices, interfacial helices, the tilt of a transmembrane helix and loop lengths. This includes trans- or intra-membrane regions of a protein, typically describing physicochemical properties of the secondary structure elements. For example, the location and size of the membrane spanning segments and intervening loop regions, transmembrane region IN/OUT orientation relative to the membrane, plus the following data for each amino acid: A Z-coordinate (the distance to the membrane center), the free energy of membrane insertion (calculated in a sliding window over the sequence) and a reliability score. The z-coordinate implies information about re-entrant helices, interfacial helices, the tilt of a transmembrane helix and loop lengths. This includes topological domains such as cytoplasmic regions in a protein.

rdfs:seeAlso

n9:Protein_superfamily

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n2:topic_2814

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obo:inSubset

n2:bio n2:topics n10:topics n10:edam

obo:hasNarrowSynonym

Protein membrane regions Protein structural domains Protein topological domains Protein folds Intramembrane regions Protein domains Protein transmembrane regions Transmembrane regions

n2:created_in

beta12orEarlier

n2:isdebtag

true true

obo:hasDefinition

Protein tertiary structural domains and folds in a protein or polypeptide chain.

obo:hasHumanReadableId

Protein_folds_and_structural_domains