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fabio:Abstract

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Bovine group A rotavirus (RVA) is considered the major cause of diarrhea in intensively reared neonatal calves. Chicken egg yolk antibodies (IgY) are efficient in protecting neonatal calves from RVA diarrhea; however, it is unclear the value of this intervention in calves once diarrhea has appeared. The aim of the present study was to evaluate the application of RVA-specific IgY as a passive treatment in those cases. The experimental groups were: G1= RVA-specific IgY treatment; G2= no Ab treatment; and G3= colostrum deprived + no Ab treatment. IgY treatment significantly reduced virus shedding, diarrhea duration and severity compared to G2 and G3 calves. However, it caused a partial suppression of systemic Ab responses to RVA that could be associated with less severe diarrhea. The oral treatment with IgY for 7 days was associated with significantly higher antibody secreting cell responses in the calves compared with the other groups of animals.

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RTT Symptoms and signs: Digestive system and abdomen Diarrhea Sanitation Waterborne diseases Virology RTTEM Conditions diagnosed by stool test Virus genera Diseases of intestines Intestinal infectious diseases Feces

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covid:b3935c8b90d9ca6671636eaae86eab9cb0295fe8