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Subject Item
n2:CMO_0001657
rdf:type
owl:Class
rdfs:label
concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (EC50)
rdfs:subClassOf
n2:CMO_0002464 n2:CMO_0001659
wdrs:describedby
n7:owl
n2:IAO_0000115
A calculated value for the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy.
obo:created_by
JSmith
obo:creation_date
2013-06-20T14:22:08Z
obo:hasDbXref
CHEBI:48432
obo:hasRelatedSynonym
angiotensin II half maximal effective concentration (EC50) AngII half maximal effective concentration Ang2 half maximal effective concentration angiotensin 2 half maximal effective concentration
obo:hasOBONamespace
clinical_measurement_ontology
obo:id
CMO:0001657