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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Use_dmy_dates> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Matter100020827> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/kegg>	"D07077"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/chembl>	"1111"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://hu.dbpedia.org/resource/Ambriszent\u00E1n> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Material114580897> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://fa.dbpedia.org/resource/\u0627\u0645\u0628\u0631\u06CC\u0632\u0646\u062A\u0627\u0646> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Vasoconstriction> .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Ambrisentan#this> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://or.dbpedia.org/resource/\u0B06\u0B2E\u0B4D\u0B2C\u0B4D\u0B30\u0B3F\u0B38\u0B47\u0B23\u0B4D\u0B1F\u0B3E\u0B28> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Chemical114806838> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Compound114818238> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://sh.dbpedia.org/resource/Ambrisentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Drug-na\u00EFve> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/pregnancyAu>	"X"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/atcPrefix>	"2.0"^^<http://dbpedia.org/datatype/nicaraguanC\u00F3rdoba> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://id.dbpedia.org/resource/Ambrisentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/c>	"22"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Update_section> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Substance100019613> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Endothelin_receptor_antagonist> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://sr.dbpedia.org/resource/Ambrisentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#label>	"Ambrisentan"@fr .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<https://global.dbpedia.org/id/3ohn5> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#label>	"Ambrisentan"@in .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Bilirubin> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/class/yago/Part113809207> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/chEBI>	"135949" .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Gilead_Sciences> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/abstract>	"\u30A2\u30F3\u30D6\u30EA\u30BB\u30F3\u30BF\u30F3\uFF08Ambrisentan\uFF09\u306F\u80BA\u9AD8\u8840\u5727\u6CBB\u7642\u85AC\u306E\u4E00\u3064\u3067\u3042\u308B\u3002A\uFF08ETA\uFF09\u9078\u629E\u7684\u3068\u3057\u3066\u4F5C\u7528\u3059\u308B\u30021\u65E51\u56DE2.5\u301C10mg\u3092\u7D4C\u53E3\u6295\u4E0E\u3059\u308B\u3068\u507D\u85AC\u3068\u6BD4\u8F03\u3057\u3066\u8010\u904B\u52D5\u8CA0\u8377\uFF086\u5206\u9593\u6B69\u884C\u8DDD\u96E2\uFF09\u304C\u6709\u610F\u306B\u6539\u5584\u3059\u308B\u3053\u3068\u304C\u4E8C\u91CD\u76F2\u691C\u8A66\u9A13\uFF08ARIES-1\u3001ARIES-2\uFF09\u3067\u793A\u3055\u308C\u305F\u3002\u5546\u54C1\u540D\u30F4\u30A9\u30EA\u30D6\u30EA\u30B9\u3002 \u7C73\u56FD\u30672007\u5E747\u6708\u306B\u80BA\u52D5\u8108\u6027\u80BA\u9AD8\u8840\u5727\u75C7\u306E\u6CBB\u7642\u85AC\u3068\u3057\u3066\u627F\u8A8D\u3055\u308C\u305F\u3002\u6B27\u5DDE\u3067\u306F2008\u5E744\u6708\u306B\u627F\u8A8D\u3055\u308C\u305F\u3002\u65E5\u672C\u3067\u306F2010\u5E747\u6708\u306B\u627F\u8A8D\u3055\u308C\u305F\u3002\u30A2\u30F3\u30D6\u30EA\u30BB\u30F3\u30BF\u30F3\u306F\u627F\u8A8D\u306B\u5148\u7ACB\u3063\u3066\u5E0C\u5C11\u75BE\u75C5\u7528\u533B\u85AC\u54C1\u306B\u6307\u5B9A\u3055\u308C\u3066\u3044\u308B\uFF08\u7C73\u56FD\uFF1A2004\u5E748\u6708\u3001\u6B27\u5DDE\uFF1A2005\u5E745\u6708\u3001\u65E5\u672C\uFF1A2013\u5E746\u6708\uFF09\u3002"@ja .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2002/07/owl#sameAs>	<http://dbpedia.org/resource/Ambrisentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#label>	"Ambrisentan"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/ontology/Drug> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://www.wikidata.org/entity/Q8386> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/legalAu>	"S4"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://en.wikipedia.org/wiki/Ambrisentan> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Bosentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/casNumber>	"177036"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/ontology/ChemicalSubstance> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/chebi>	"135949"^^<http://www.w3.org/2001/XMLSchema#integer> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/bioavailability>	"Undetermined"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/stdinchi>	"1"^^<http://www.w3.org/2001/XMLSchema#integer> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://purl.org/dc/terms/subject>	<http://dbpedia.org/resource/Category:Gilead_Sciences> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/legalUs>	"Rx-only"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/abstract>	"L'ambrisentan est un inhibiteur des r\u00E9cepteurs de l'endoth\u00E9line utilis\u00E9 comme m\u00E9dicament par voie orale dans le traitement de l'hypertension art\u00E9rielle pulmonaire."@fr .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/PhysicalEntity100001930> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/verifiedrevid>	"437179007"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Ambrisentan>	<http://purl.org/dc/terms/subject>	<http://dbpedia.org/resource/Category:Orphan_drugs> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/chEMBL>	"1111" .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Orphan_drugs> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:PAH_rx> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2007/05/powder-s#describedby>	<http://localhost:8890/about/id/entity/http/dbpedia.org/resource/Drug> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Endothelin_1> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/alternativeName>	"Letairis, Volibris, Pulmonext"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/routesOfAdministration>	"Oral"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Endothelin_receptor> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Tadalafil> .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/List_of_signaling_peptide/protein_receptor_modulators> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/class/yago/MolecularFormula106817173> .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Darusentan> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension. The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2). Like all endothelin receptor antagonists, Ambrisentan is contraindicated in pregnant women as well as those who are trying to become pregnant, due to the potential for teratogenic effects on the fetus. Patients who are on the Ambrisen"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/C22H22N2O4> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/kegg>	"D07077" .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/abstract>	"Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension. The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2). Like all endothelin receptor antagonists, Ambrisentan is contraindicated in pregnant women as well as those who are trying to become pregnant, due to the potential for teratogenic effects on the fetus. Patients who are on the Ambrisentan must enroll in the Ambrisentan (Letairis) REMS Program. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), and designated an orphan drug, for the treatment of pulmonary hypertension."@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/legalCa>	"Rx-only"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Category:Acetic_acids> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/width>	"200"^^<http://www.w3.org/2001/XMLSchema#integer> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/tradename>	"Letairis, Volibris, Pulmonext"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://umbel.org/umbel/rc/DrugProduct> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/pubchem>	"6918493"^^<http://www.w3.org/2001/XMLSchema#integer> .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Macitentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/legalStatus>	"Rx-only"@en .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Base114618253> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Statement106722453> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Endothelin> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/licenceUs>	"Ambrisentan"@en .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/legalEu>	"Rx-only"@en .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/abstract>	"Ambrisentan adalah obat golongan antagonis reseptor endotelin. Obat ini bekerja secara selektif untuk reseptor endotelin tipe A (ETA). Mekanisme obat ini bekerja dengan menghambat aktivitas endotelin. Endotelin adalah zat di dalam tubuh yang menyebabkan penyempitan pembuluh darah dan menyebabkan peningkatan aliran dan tekanan darah. Obat ini digunakan dalam pengobatan hipertensi paru. Ambrisentan dapat meningkatkan kemampuan penderita hipertensi paru untuk beraktivitas dan memperlambat perburukan penyakit. Obat ini tidak bisa diberikan pada ibu hamil karena bersifat teratogenik. Efek samping yang paling sering dilaporkan adalah bengkak pada wajah, tangan dan kaki, peningkatan berat badan, sensasi kesemutan atau geli pada kaki dan tangan serta pusing."@in .
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<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Ambrisentan ist ein Arzneistoff aus der Gruppe der Endothelin-Rezeptorantagonisten. Er wird zur Behandlung einer seltenen Form des Bluthochdrucks verwendet, bei der Blutdruck in den Blutgef\u00E4\u00DFen erh\u00F6ht ist, durch die das Blut vom Herzen in die Lungen flie\u00DFt (Lungenbluthochdruck, pulmonal-arterielle Hypertonie (PAH) der WHO-Funktionsklassen II und III). F\u00FCr dieses Anwendungsgebiet ist er unter dem Handelsnamen Volibris\u00AE (Hersteller GlaxoSmithKline (GSK)) seit 2008 in der Europ\u00E4ischen Union und in der Schweiz zugelassen."@de .
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<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Quintessence114847103> .
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<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#comment>	"L'ambrisentan est un inhibiteur des r\u00E9cepteurs de l'endoth\u00E9line utilis\u00E9 comme m\u00E9dicament par voie orale dans le traitement de l'hypertension art\u00E9rielle pulmonaire."@fr .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/drugbank>	"DB06403" .
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<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageExternalLink>	<https://druginfo.nlm.nih.gov/drugportal/name/ambrisentan> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/abstract>	"Ambrisentan ist ein Arzneistoff aus der Gruppe der Endothelin-Rezeptorantagonisten. Er wird zur Behandlung einer seltenen Form des Bluthochdrucks verwendet, bei der Blutdruck in den Blutgef\u00E4\u00DFen erh\u00F6ht ist, durch die das Blut vom Herzen in die Lungen flie\u00DFt (Lungenbluthochdruck, pulmonal-arterielle Hypertonie (PAH) der WHO-Funktionsklassen II und III). F\u00FCr dieses Anwendungsgebiet ist er unter dem Handelsnamen Volibris\u00AE (Hersteller GlaxoSmithKline (GSK)) seit 2008 in der Europ\u00E4ischen Union und in der Schweiz zugelassen. Ambrisentan ist, wie auch die Endothelin-Rezeptorantagonisten Bosentan und Sitaxentan, als Orphan-Arzneimittel klassifiziert."@de .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Ambrisentan adalah obat golongan antagonis reseptor endotelin. Obat ini bekerja secara selektif untuk reseptor endotelin tipe A (ETA). Mekanisme obat ini bekerja dengan menghambat aktivitas endotelin. Endotelin adalah zat di dalam tubuh yang menyebabkan penyempitan pembuluh darah dan menyebabkan peningkatan aliran dan tekanan darah. Obat ini digunakan dalam pengobatan hipertensi paru. Ambrisentan dapat meningkatkan kemampuan penderita hipertensi paru untuk beraktivitas dan memperlambat perburukan penyakit."@in .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Pulmonary_hypertension> .
<http://dbpedia.org/resource/Ambrisentan>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/ATCvet_code_QC02KX02> .
<http://dbpedia.org/resource/Ambrisentan>	<http://dbpedia.org/property/wikiPageUsesTemplate>	<http://dbpedia.org/resource/Template:Short_description> .
<http://dbpedia.org/resource/Ambrisentan>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Vasodilation> .