<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Teixobactin> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/SN2_reaction> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageExternalLink>	<http://www.nature.com/scitable/topicpage/the-role-of-methylation-in-gene-expression-1070> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Alkylrandomization> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Electrophile> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Mesoniviridae> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/File:Histone_Methyltransferases.png> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Acetogenesis> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/BAH_domain> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/File:Methylxanthin_(R1,_R2,_R3).svg> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/File:N-a_methyltransferases.png> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<http://localhost:8890/about/id/entity/http/dbpedia.org/resource/Non-coding_RNA> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/File:Non_SAM_methyl_donors.png> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/File:PNMT_2.png> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/File:SET7_9.png> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/depiction>	<http://commons.wikimedia.org/wiki/Special:FilePath/5_methylcytosine_methyl_highlight.png> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/M6A> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Histone> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Gene_silencing> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Phycodnaviridae> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Tomas_Lindahl> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Linezolid> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Arginine> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Epitranscriptome> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageLength>	"26083"^^<http://www.w3.org/2001/XMLSchema#nonNegativeInteger> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"\u0646\u0627\u0642\u0644\u0629 \u0627\u0644\u0645\u064A\u062B\u064A\u0644 (\u0628\u0627\u0644\u0625\u0646\u062C\u0644\u064A\u0632\u064A\u0629: Methyltransferase)\u200F \u0647\u064A \u0639\u0627\u0626\u0644\u0629 \u0643\u0628\u064A\u0631\u0629 \u0645\u0646 \u0627\u0644\u0625\u0646\u0632\u064A\u0645\u0627\u062A \u062A\u0642\u0648\u0645 \u0628\u0645\u062B\u064A\u0644\u0629 \u0631\u0643\u0627\u0626\u0632\u0647\u0627\u060C \u0648\u064A\u0645\u0643\u0646 \u062A\u0642\u0633\u064A\u0645\u0647\u0627 \u0625\u0644\u0649 \u0623\u0642\u0633\u0627\u0645 \u0641\u0631\u0639\u064A\u0629 \u0639\u062F\u064A\u062F\u0629 \u062D\u0633\u0628 \u062E\u0635\u0627\u0626\u0635\u0647\u0627 \u0627\u0644\u0628\u0646\u064A\u0648\u064A\u0629. \u0623\u0634\u0647\u0631 \u0623\u0642\u0633\u0627\u0645 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0647\u0648 \u0627\u0644\u0642\u0633\u0645 1 \u0627\u0644\u0630\u064A \u062A\u062D\u062A\u0648\u064A \u062C\u0645\u064A\u0639 \u0627\u0644\u0625\u0646\u0632\u064A\u0645\u0627\u062A \u0641\u064A\u0647 \u0639\u0644\u0649 \u0644\u0644\u0627\u0631\u062A\u0628\u0627\u0637 \u0628\u0640 (SAM\u060C \u0633\u0627\u0645). \u064A\u062D\u062A\u0648\u064A \u0627\u0644\u0642\u0633\u0645 2 \u0645\u0646 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 SET \u0643\u0645\u062B\u0627\u0644 \u0646\u0637\u0627\u0642 SET \u0644\u0646\u0627\u0642\u0644\u0629 \u0645\u064A\u062B\u064A\u0644 \u0627\u0644\u0647\u0633\u062A\u0648\u0646. \u0648\u0627\u0644\u0642\u0633\u0645 3 \u0645\u0646 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0644\u0647\u0627 \u0648\u0638\u064A\u0641\u0629 \u0645\u0631\u062A\u0628\u0637\u0629 \u0628\u0627\u0644\u063A\u0634\u0627\u0621. \u064A\u0645\u0643\u0646 \u0623\u0646 \u062A\u064F\u0642\u0633\u064E\u0651\u0645 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0643\u0630\u0644\u0643 \u0625\u0644\u0649 \u0623\u0646\u0648\u0627\u0639 \u0645\u062E\u062A\u0644\u0641\u0629 \u062D\u0633\u0628 \u0627\u0644\u0631\u0643\u0627\u0626\u0632 \u0623\u062B\u0646\u0627\u0621 \u062A\u0641\u0627\u0639\u0644\u0627\u062A \u0646\u0642\u0644 \u0627\u0644\u0645\u064A\u062B\u064A\u0644. \u062A\u0634\u0645\u0644 \u0647\u0630\u0647 \u0627\u0644\u0623\u0646\u0648\u0627\u0639\u060C \u0646\u0627\u0642\u0644\u0627\u062A \u0645\u064A\u062B\u064A\u0644 \u0627\u0644\u0628\u0631\u0648\u062A\u064A\u0646\u060C \u0646\u0627\u0642\u0644\u0627\u062A \u0645\u064A\u062B\u064A\u0644 \u0627\u0644\u062F\u0646\u0627/ \u0627\u0644\u0631\u0646\u0627\u060C \u0646\u0627\u0642\u0644\u0627\u062A \u0645\u064A\u062B\u064A\u0644 \u0627\u0644\u0646\u0627\u062A\u062C \u0627\u0644\u0637\u0628\u064A\u0639\u064A\u060C \u0648\u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u063A\u064A\u0631 \u0627\u0644\u0645\u0639\u062A\u0645\u062F\u0629 \u0639\u0644\u0649 SAM. \u200F SAM \u0647\u0648 \u0645\u0627\u0646\u062D \u0645\u064A\u062B\u064A\u0644 \u0643\u0644\u0627\u0633\u064A\u0643\u064A\u060C \u0644\u0643\u0646 \u0644\u0648\u062D\u0638\u062A \u0645\u0627\u0646\u062D\u0627\u062A \u0645\u064A\u062B\u064A\u0644 \u0623\u062E\u0631\u0649 \u0637\u0628\u064A\u0639\u064A\u0629. \u0627\u0644\u0622\u0644\u064A\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0641\u064A \u0646\u0642\u0644 \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0647\u0648 \u0627\u0644\u0647\u062C\u0648\u0645 \u0627\u0644\u0645\u062D\u0628 \u0644\u0644\u0646\u0648\u0627\u0629 \u0627\u0644\u0645\u0634\u0627\u0628\u0647 \u0644\u0640 \u0623\u064A\u0646 \u064A\u0639\u0645\u0644 \u0643\u0628\u0631\u064A\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0648\u0646\u064A\u0646 \u0643\u0645\u062D\u0628 \u0644\u0644\u0646\u0648\u0627\u0629 \u0648\u064A\u0646\u0642\u0644 \u0645\u062C\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0625\u0644\u0649 \u0631\u0643\u064A\u0632\u0629 \u0627\u0644\u0625\u0646\u0632\u064A\u0645. \u064A\u064F\u062D\u0648\u064E\u0651\u0644 SAM \u0625\u0644\u0649 (SAH) \u0623\u062B\u0646\u0627\u0621 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064A\u0629. \u0643\u0633\u0631 \u0631\u0627\u0628\u0637\u0629 \u0633\u0627\u0645-\u0645\u064A\u062B\u064A\u0644 \u0648\u062A\u0643\u0648\u064A\u0646 \u0627\u0644\u0631\u0627\u0628\u0637\u0629 \u0631\u0643\u064A\u0632\u0629-\u0645\u064A\u062B\u064A\u0644 \u064A\u062D\u062F\u062B \u0628\u0627\u0644\u062A\u0642\u0631\u064A\u0628 \u0641\u064A \u0622\u0646 \u0648\u0627\u062D\u062F. \u064A\u0648\u062C\u062F \u0647\u0630\u0627 \u0627\u0644\u062A\u0641\u0627\u0639\u0644 \u0627\u0644\u0625\u0646\u0632\u064A\u0645\u064A \u0641\u064A \u0627\u0644\u0639\u062F\u064A\u062F \u0645\u0646 \u0627\u0644\u0645\u0633\u0627\u0631\u0627\u062A \u0648\u0644\u0647 \u062F\u0648\u0631 \u0641\u064A \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u062C\u064A\u0646\u064A\u0629 \u0648\u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0623\u064A\u0636."@ar .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Centromere> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/O-methyltransferase> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/NSUN2> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Drug_discovery> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/class/yago/Protein114728724> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/P53> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Drug_metabolism> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/TRNA> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/COMPASS_complex> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/KMT2D> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/KMT2A> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Drug_development> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/TmRNA> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Plasmid> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Drug_discovery> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/class/yago/Chemical114806838> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Rossmann_fold> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Arsenic_biochemistry> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/L-Tryptophan_decarboxylase> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageExternalLink>	<http://biowiki.ucdavis.edu/Biochemistry/Catalysis/METHODS_OF_CATALYSIS/Metal_Ion_%28or_Electrostatic%29_Catalysis> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Transcription_(genetics)> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/PhysicalEntity100001930> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Matter100020827> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/RadC_RNA_motif> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Molecule114682133> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2007/05/powder-s#describedby>	<https://covidontheweb.inria.fr:4443/about/id/entity/http/dbpedia.org/resource/Conserved_sequence> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Macromolecule114944888> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Material114580897> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Chemical114806838> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Compound114818238> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Guanidine> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Methionine_synthase> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/23S_rRNA_(guanine2535-N1)-methyltransferase> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Unit109465459> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Acid_catalysis> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Substance100019613> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Thing100002452> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Group100031264> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/OrganicCompound114727670> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/1999/02/22-rdf-syntax-ns#type>	<http://dbpedia.org/class/yago/Protein114728724> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Methanethiol> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Protein_biosynthesis> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/William_Lipscomb> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/23S_rRNA_(adenine2085-N6)-dimethyltransferase> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"Metylotransferaza \u2013 enzym przenosz\u0105cy reszt\u0119 metylow\u0105 pomi\u0119dzy zwi\u0105zkami uczestnicz\u0105cymi w reakcji, zmieniaj\u0105c w ten spos\u00F3b ich dzia\u0142anie."@pl .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageWikiLink>	<http://dbpedia.org/resource/Mutation> .
<http://dbpedia.org/resource/Methyltransferase>	<http://xmlns.com/foaf/0.1/topic>	<http://dbpedia.org/resource/Organic_Lake_virophage> .
<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/wikiPageExternalLink>	<https://web.archive.org/web/20071029191926/http:/www.flintbox.com/technology.asp%3Fpage=2941> .
<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Les m\u00E9thyltransf\u00E9rases sont un groupe d'enzymes de la famille des transf\u00E9rases qui, comme leur nom l'indique, transf\u00E8rent un groupe m\u00E9thyle d'un donneur \u00E0 un accepteur. Les m\u00E9thyltransf\u00E9rases forment la sous-classe EC 2.1.1 dans la nomenclature EC. La m\u00E9thylation se produit couramment sur les bases nucl\u00E9iques de l'ADN ou sur des acides amin\u00E9s d'une prot\u00E9ine. De nombreuses m\u00E9thytransferases, les m\u00E9thylases SAM-d\u00E9pendantes, utilisent la S-ad\u00E9nosylm\u00E9thionine (SAM) comme donneur, o\u00F9 le groupe m\u00E9thyle est activ\u00E9 par une liaison \u00E0 un atome de soufre."@fr .
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<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"Una metiltransferasi \u00E8 un enzima appartenente alla classe delle transferasi, in grado di trasferire un gruppo metile da una molecola donatrice ad un accettore. Secondo la classificazione EC, tutte le metiltransferasi sono raggruppate nella sotto-sottoclasse EC 2.1.1. La metilazione mediata da questi enzimi ha solitamente luogo presso le basi azotate del DNA o sugli amminoacidi che compongono le proteine. La fonte di metili utilizzata dalle metiltransferasi \u00E8 il metile reattivo legato allo zolfo della S-adenosil metionina (SAM). La metilazione del DNA \u00E8 spesso utilizzata per silenziare e regolare i geni senza modificarne la sequenza. Tale metilazione, possibile grazie alla DNA metiltransferasi, avviene presso i residui di citosina ed \u00E8 necessaria per molti processi connessi allo sviluppo embrionale dei mammiferi. Mutanti privi di tale enzima si sono rivelati non vitali. La metilazione \u00E8 stata anche correlata allo sviluppo del cancro: la metilazione di geni oncosoppressori, infatti, promuove la tumorigenesi e la metastasi. Le metiltransferasi sito-specifiche presentano specificit\u00E0 di sequenza metilata, spesso identiche a quelle di alcuni enzimi di restrizione. La metilazione, in questi casi, pu\u00F2 aver la funzione di proteggere il DNA dal taglio enzimatico, dal momento che gli enzimi di restrizione non sono in grado di tagliare sequenze metilate. La metilazione degli amminoacidi durante la formazione delle proteine porta concretamente ad un aumento del numero di differenti residui, con una conseguente diversit\u00E0 di funzioni. Le metilazioni hanno luogo presso gli atomi di azoto delle catene laterali o presso l'estremit\u00E0 N-terminale. In entrambi i casi, si tratta di reazioni solitamente irreversibili."@it .
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<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C(\uC601\uC5B4: methyltransferase) \uB610\uB294 \uBA54\uD2F8\uD2B8\uB79C\uC2A4\uD37C\uB808\uC774\uC2A4\uB294 \uAE30\uC9C8\uC744 \uBA54\uD2F8\uD654\uD558\uB294 \uBC18\uC751\uC744 \uCD09\uB9E4\uD558\uB294 \uD6A8\uC18C\uC774\uBA70, \uAD6C\uC870\uC801 \uD2B9\uC9D5\uC5D0 \uB530\uB77C \uC5EC\uB7EC \uD558\uC704 \uBD80\uB958\uB85C \uB098\uB20C \uC218 \uC788\uB294 \uD6A8\uC18C\uB4E4\uC758 \uD070 \uADF8\uB8F9\uC774\uB2E4. \uBA54\uD2F8\uD654\uD6A8\uC18C(\uC601\uC5B4: methylase) \uB610\uB294 \uBA54\uD2F8\uB808\uC774\uC2A4\uB77C\uACE0\uB3C4 \uD55C\uB2E4. \uAC00\uC7A5 \uC77C\uBC18\uC801\uC778 \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uC758 \uBD80\uB958\uB294 \uD074\uB798\uC2A4 I\uC774\uBA70, \uD074\uB798\uC2A4 I\uC740 S-\uC544\uB370\uB178\uC2E4\uBA54\uD2F0\uC624\uB2CC(SAM)\uC5D0 \uACB0\uD569\uD558\uAE30 \uC704\uD55C \uC744 \uD3EC\uD568\uD558\uACE0 \uC788\uB2E4. \uD074\uB798\uC2A4 II \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uB294 SET \uB3C4\uBA54\uC778\uC744 \uD3EC\uD568\uD558\uBA70, \uC608\uB85C\uB294 \uC758 SET \uB3C4\uBA54\uC778\uC774 \uC788\uB2E4. \uD074\uB798\uC2A4 III \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uB294 \uB9C9\uC5D0 \uACB0\uD569\uB418\uC5B4 \uC788\uB2E4. \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uB294 \uB610\uD55C \uBA54\uD2F8\uAE30 \uC804\uC774 \uBC18\uC751\uC5D0\uC11C \uB2E4\uB978 \uAE30\uC9C8\uB4E4\uC744 \uC0AC\uC6A9\uD558\uB294 \uB2E4\uB978 \uC720\uD615\uC73C\uB85C \uAD6C\uBD84\uB420 \uC218 \uC788\uB2E4."@ko .
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<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Methyltransferasen oder Methylasen sind Enzyme in allen Lebewesen, die ihre Substrate methylieren, das hei\u00DFt, sie \u00FCbertragen eine Methylgruppe auf andere Biomolek\u00FCle. Diese Reaktion ist Teil ganz unterschiedlicher Stoffwechselwege, insbesondere bei der Biosynthese der Cobalamine, Menachinone, von Porphyrin, Methionin und dTTP. Neben diversen Synthesewegen helfen Methyltransferasen allgemein beim Prozessieren von genetischer Information, so beim Verarbeiten von ribosomaler RNA, bei der DNA-Methylierung und anderer Methoden der Regulation der Transkription, beim mRNA-Capping und der Modifizierung von tRNA. Es gibt N-Methyltransferasen, und die vergleichsweise selteneren ."@de .
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<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Metylotransferaza \u2013 enzym przenosz\u0105cy reszt\u0119 metylow\u0105 pomi\u0119dzy zwi\u0105zkami uczestnicz\u0105cymi w reakcji, zmieniaj\u0105c w ten spos\u00F3b ich dzia\u0142anie."@pl .
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<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2000/01/rdf-schema#comment>	"\u0646\u0627\u0642\u0644\u0629 \u0627\u0644\u0645\u064A\u062B\u064A\u0644 (\u0628\u0627\u0644\u0625\u0646\u062C\u0644\u064A\u0632\u064A\u0629: Methyltransferase)\u200F \u0647\u064A \u0639\u0627\u0626\u0644\u0629 \u0643\u0628\u064A\u0631\u0629 \u0645\u0646 \u0627\u0644\u0625\u0646\u0632\u064A\u0645\u0627\u062A \u062A\u0642\u0648\u0645 \u0628\u0645\u062B\u064A\u0644\u0629 \u0631\u0643\u0627\u0626\u0632\u0647\u0627\u060C \u0648\u064A\u0645\u0643\u0646 \u062A\u0642\u0633\u064A\u0645\u0647\u0627 \u0625\u0644\u0649 \u0623\u0642\u0633\u0627\u0645 \u0641\u0631\u0639\u064A\u0629 \u0639\u062F\u064A\u062F\u0629 \u062D\u0633\u0628 \u062E\u0635\u0627\u0626\u0635\u0647\u0627 \u0627\u0644\u0628\u0646\u064A\u0648\u064A\u0629. \u0623\u0634\u0647\u0631 \u0623\u0642\u0633\u0627\u0645 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0647\u0648 \u0627\u0644\u0642\u0633\u0645 1 \u0627\u0644\u0630\u064A \u062A\u062D\u062A\u0648\u064A \u062C\u0645\u064A\u0639 \u0627\u0644\u0625\u0646\u0632\u064A\u0645\u0627\u062A \u0641\u064A\u0647 \u0639\u0644\u0649 \u0644\u0644\u0627\u0631\u062A\u0628\u0627\u0637 \u0628\u0640 (SAM\u060C \u0633\u0627\u0645). \u064A\u062D\u062A\u0648\u064A \u0627\u0644\u0642\u0633\u0645 2 \u0645\u0646 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 SET \u0643\u0645\u062B\u0627\u0644 \u0646\u0637\u0627\u0642 SET \u0644\u0646\u0627\u0642\u0644\u0629 \u0645\u064A\u062B\u064A\u0644 \u0627\u0644\u0647\u0633\u062A\u0648\u0646. \u0648\u0627\u0644\u0642\u0633\u0645 3 \u0645\u0646 \u0646\u0627\u0642\u0644\u0627\u062A \u0627\u0644\u0645\u064A\u062B\u064A\u0644 \u0644\u0647\u0627 \u0648\u0638\u064A\u0641\u0629 \u0645\u0631\u062A\u0628\u0637\u0629 \u0628\u0627\u0644\u063A\u0634\u0627\u0621. \u064A\u0648\u062C\u062F \u0647\u0630\u0627 \u0627\u0644\u062A\u0641\u0627\u0639\u0644 \u0627\u0644\u0625\u0646\u0632\u064A\u0645\u064A \u0641\u064A \u0627\u0644\u0639\u062F\u064A\u062F \u0645\u0646 \u0627\u0644\u0645\u0633\u0627\u0631\u0627\u062A \u0648\u0644\u0647 \u062F\u0648\u0631 \u0641\u064A \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u062C\u064A\u0646\u064A\u0629 \u0648\u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0623\u064A\u0636."@ar .
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<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"\uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C(\uC601\uC5B4: methyltransferase) \uB610\uB294 \uBA54\uD2F8\uD2B8\uB79C\uC2A4\uD37C\uB808\uC774\uC2A4\uB294 \uAE30\uC9C8\uC744 \uBA54\uD2F8\uD654\uD558\uB294 \uBC18\uC751\uC744 \uCD09\uB9E4\uD558\uB294 \uD6A8\uC18C\uC774\uBA70, \uAD6C\uC870\uC801 \uD2B9\uC9D5\uC5D0 \uB530\uB77C \uC5EC\uB7EC \uD558\uC704 \uBD80\uB958\uB85C \uB098\uB20C \uC218 \uC788\uB294 \uD6A8\uC18C\uB4E4\uC758 \uD070 \uADF8\uB8F9\uC774\uB2E4. \uBA54\uD2F8\uD654\uD6A8\uC18C(\uC601\uC5B4: methylase) \uB610\uB294 \uBA54\uD2F8\uB808\uC774\uC2A4\uB77C\uACE0\uB3C4 \uD55C\uB2E4. \uAC00\uC7A5 \uC77C\uBC18\uC801\uC778 \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uC758 \uBD80\uB958\uB294 \uD074\uB798\uC2A4 I\uC774\uBA70, \uD074\uB798\uC2A4 I\uC740 S-\uC544\uB370\uB178\uC2E4\uBA54\uD2F0\uC624\uB2CC(SAM)\uC5D0 \uACB0\uD569\uD558\uAE30 \uC704\uD55C \uC744 \uD3EC\uD568\uD558\uACE0 \uC788\uB2E4. \uD074\uB798\uC2A4 II \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uB294 SET \uB3C4\uBA54\uC778\uC744 \uD3EC\uD568\uD558\uBA70, \uC608\uB85C\uB294 \uC758 SET \uB3C4\uBA54\uC778\uC774 \uC788\uB2E4. \uD074\uB798\uC2A4 III \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uB294 \uB9C9\uC5D0 \uACB0\uD569\uB418\uC5B4 \uC788\uB2E4. \uBA54\uD2F8\uAE30\uC804\uC774\uD6A8\uC18C\uB294 \uB610\uD55C \uBA54\uD2F8\uAE30 \uC804\uC774 \uBC18\uC751\uC5D0\uC11C \uB2E4\uB978 \uAE30\uC9C8\uB4E4\uC744 \uC0AC\uC6A9\uD558\uB294 \uB2E4\uB978 \uC720\uD615\uC73C\uB85C \uAD6C\uBD84\uB420 \uC218 \uC788\uB2E4."@ko .
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<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"Les m\u00E9thyltransf\u00E9rases sont un groupe d'enzymes de la famille des transf\u00E9rases qui, comme leur nom l'indique, transf\u00E8rent un groupe m\u00E9thyle d'un donneur \u00E0 un accepteur. Les m\u00E9thyltransf\u00E9rases forment la sous-classe EC 2.1.1 dans la nomenclature EC. La m\u00E9thylation se produit couramment sur les bases nucl\u00E9iques de l'ADN ou sur des acides amin\u00E9s d'une prot\u00E9ine. De nombreuses m\u00E9thytransferases, les m\u00E9thylases SAM-d\u00E9pendantes, utilisent la S-ad\u00E9nosylm\u00E9thionine (SAM) comme donneur, o\u00F9 le groupe m\u00E9thyle est activ\u00E9 par une liaison \u00E0 un atome de soufre."@fr .
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<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"Methyltransferasen oder Methylasen sind Enzyme in allen Lebewesen, die ihre Substrate methylieren, das hei\u00DFt, sie \u00FCbertragen eine Methylgruppe auf andere Biomolek\u00FCle. Diese Reaktion ist Teil ganz unterschiedlicher Stoffwechselwege, insbesondere bei der Biosynthese der Cobalamine, Menachinone, von Porphyrin, Methionin und dTTP. Neben diversen Synthesewegen helfen Methyltransferasen allgemein beim Prozessieren von genetischer Information, so beim Verarbeiten von ribosomaler RNA, bei der DNA-Methylierung und anderer Methoden der Regulation der Transkription, beim mRNA-Capping und der Modifizierung von tRNA. Es gibt N-Methyltransferasen, und die vergleichsweise selteneren ."@de .
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<http://dbpedia.org/resource/Methyltransferase>	<http://www.w3.org/2000/01/rdf-schema#comment>	"Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. The most common class of methyltransferases is class I, all of which contain a Rossmann fold for binding S-Adenosyl methionine (SAM). Class II methyltransferases contain a SET domain, which are exemplified by SET domain histone methyltransferases, and class III methyltransferases, which are membrane associated. Methyltransferases can also be grouped as different types utilizing different substrates in methyl transfer reactions. These types include protein methyltransferases, DNA/RNA methyltransferases, natural product methyltransferases, and non-SAM dependent methyltransferases. SAM is the classical methyl donor for methyltransfera"@en .
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<http://dbpedia.org/resource/Methyltransferase>	<http://dbpedia.org/ontology/abstract>	"Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features. The most common class of methyltransferases is class I, all of which contain a Rossmann fold for binding S-Adenosyl methionine (SAM). Class II methyltransferases contain a SET domain, which are exemplified by SET domain histone methyltransferases, and class III methyltransferases, which are membrane associated. Methyltransferases can also be grouped as different types utilizing different substrates in methyl transfer reactions. These types include protein methyltransferases, DNA/RNA methyltransferases, natural product methyltransferases, and non-SAM dependent methyltransferases. SAM is the classical methyl donor for methyltransferases, however, examples of other methyl donors are seen in nature. The general mechanism for methyl transfer is a SN2-like nucleophilic attack where the methionine sulfur serves as the leaving group and the methyl group attached to it acts as the electrophile that transfers the methyl group to the enzyme substrate. SAM is converted to S-Adenosyl homocysteine (SAH) during this process. The breaking of the SAM-methyl bond and the formation of the substrate-methyl bond happen nearly simultaneously. These enzymatic reactions are found in many pathways and are implicated in genetic diseases, cancer, and metabolic diseases. Another type of methyl transfer is the radical S-Adenosyl methionine (SAM) which is the methylation of unactivated carbon atoms in primary metabolites, proteins, lipids, and RNA."@en .